Evidence map›Paper›PMID 36711859›Full record

ArticlebioRxiv : the preprint server for biology2023

Ribosome rescue factor PELOTA modulates translation start site choice and protein isoform levels of transcription factor C/EBP

Samantha G Fernandez, Lucas Ferguson, Nicholas T Ingolia

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Samantha G FernandezDepartment of Molecular and Cell Biology, University of California, Berkeley.
Lucas FergusonDepartment of Molecular and Cell Biology, University of California, Berkeley.
Nicholas T IngoliaDepartment of Molecular and Cell Biology, University of California, Berkeley.
University of California, Berkeley · USQB3 · US

Funding

Molecular Basis and Cellular Roles of Translational RegulationDP2CA195768 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI INGOLIA, NICHOLAS T · 2014 to 2014
$2.4M
Functional genomics of the dynamic molecular network controlling mRNA translation and decayR01GM130996 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI INGOLIA, NICHOLAS T · 2019 to 2022
$1.2M
Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
NCI NIH HHS DP2 CA195768NIGMS NIH HHS R01 GM130996NIH HHS S10 OD018174
6 · The paper itself

Abstract

Translation initiation at alternative start sites can dynamically control the synthesis of two or more functionally distinct protein isoforms from a single mRNA. Alternate isoforms of the hematopoietic transcription factor CCAAT-enhancer binding protein

Identifiers

PMID36711859
PMCPMC9882168
OpenAlexW4317392252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.