Evidence map›Paper›PMID 36711801›Full record

ArticlebioRxiv : the preprint server for biology2023

Preterm birth accelerates the maturation of spontaneous and resting activity in the visual cortex.

Isabelle F Witteveen, Emily McCoy, Troy D Holsworth, Catherine Z Shen, Winnie Chang, Madelyn G Nance, Allison R Belkowitz, Avery Dougald, Meghan H Puglia, Adema Ribic

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Isabelle F WitteveenDepartment of Psychology, College and Graduate School of Arts and Sciences, University of Virginia, Charlottesville, VA 22904.
Emily McCoyDepartment of Psychology, College and Graduate School of Arts and Sciences, University of Virginia, Charlottesville, VA 22904.
Troy D HolsworthDepartment of Psychology, College and Graduate School of Arts and Sciences, University of Virginia, Charlottesville, VA 22904.
Catherine Z ShenDepartment of Psychology, College and Graduate School of Arts and Sciences, University of Virginia, Charlottesville, VA 22904.
Winnie ChangDepartment of Neurology, School of Medicine, University of Virginia, Charlottesville, VA 22903.
Madelyn G NanceDepartment of Neurology, School of Medicine, University of Virginia, Charlottesville, VA 22903.
Allison R BelkowitzDepartment of Neurology, School of Medicine, University of Virginia, Charlottesville, VA 22903.
Avery DougaldDepartment of Neurology, School of Medicine, University of Virginia, Charlottesville, VA 22903.
Meghan H PugliaProgram in Fundamental Neuroscience, University of Virginia, Charlottesville, VA 22903.
Adema RibicDepartment of Psychology, College and Graduate School of Arts and Sciences, University of Virginia, Charlottesville, VA 22904.
University of Virginia · US

Funding

Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
Temperodynamic neural variability as an early-emerging biomarker of autism spectrum disordersK01MH125173 · NIMH · UNIVERSITY OF VIRGINIA · PI PUGLIA, MEGHAN H · 2021 to 2025
$914k
NCATS NIH HHS KL2 TR003016NIMH NIH HHS K01 MH125173
6 · The paper itself

Abstract

Prematurity is among the leading risks for poor neurocognitive outcomes. The brains of preterm infants show alterations in structure and electrical activity, but the underlying circuit mechanisms are unclear. To address this, we performed a cross-species study of the electrophysiological activity in the visual cortices of prematurely born infants and mice. Using electroencephalography (EEG) in a sample of healthy preterm (N=29) and term (N=28) infants, we found that the maturation of the aperiodic EEG component was accelerated in the preterm cohort, with a significantly flatter 1/f slope when compared to the term infants. The flatter slope was a result of decreased spectral power in the theta and alpha bands and was correlated with the degree of prematurity. To determine the circuit and cellular changes that potentially mediate the changes in 1/f slope after preterm birth, we used

Identifiers

PMID36711801
PMCPMC9882279
OpenAlexW4317678014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.