Evidence map›Paper›PMID 36711775›Full record

ArticlebioRxiv : the preprint server for biology2023

Multiple

Vladimir Lažetić, Michael J Blanchard, Theresa Bui, Emily R Troemel

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vladimir LažetićSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Michael J BlanchardSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Theresa BuiSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Emily R TroemelSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
University of California San Diego · US

Funding

The Intracellular Pathogen Response Triggers Defense Against Co-evolved PathogensR01GM114139 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2015 to 2026
$3.1M
Probing organismal proteostasis through the response to intracellular infectionR01AG052622 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2017 to 2026
$2.7M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
NIA NIH HHS R01 AG052622NIGMS NIH HHS R01 GM114139NIH HHS S10 OD026929
6 · The paper itself

Abstract

The immune system continually battles against pathogen-induced pressures, which often leads to the evolutionary expansion of immune gene families in a species-specific manner. For example, the AUTHOR SUMMARY: Immune responses to pathogens induce extensive rewiring of host physiology. In the short term, these changes are generally beneficial as they can promote resistance against infection. However, prolonged activation of immune responses can have serious negative consequences on host health, including impaired organismal development and fitness. Therefore, the balance between activating the immune system and promoting development must be precisely regulated. In this study, we used genetics to identify a gene in the roundworm

Identifiers

PMID36711775
PMCPMC9882112
OpenAlexW4317381224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.