Evidence map›Paper›PMID 36711744›Full record

ArticlebioRxiv : the preprint server for biology2024

Defining the contribution of microRNA-specific slicing Argonautes in animals.

Anisha Pal, Vaishnav Vasudevan, Francois Houle, Michael Lantin, Katherine A Maniates, Miguel Quevillon Huberdeau, Allison Abbott, Martin J Simard

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anisha Pal
Vaishnav Vasudevan
Francois Houle
Michael Lantin
Katherine A Maniates
Miguel Quevillon Huberdeau
Allison Abbott
Université Laval · CAMarquette University · USRutgers, The State University of New Jersey · US

Funding

IRACDA at Rutgers: INSPIRE Postdoctoral Training ProgramK12GM093854 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Detlev Boison, Gary A. Brewer · 2010 to 2026
$14.7M
Illumination system for Nikon Eclipse 80i for fluorescence microscopy of C. elegansR15GM126458 · NIGMS · MARQUETTE UNIVERSITY · PI ABBOTT, ALLISON LYNN · 2017 to 2023
$918k
NIGMS NIH HHS K12 GM093854NIGMS NIH HHS R15 GM126458
6 · The paper itself

Abstract

microRNAs regulate gene expression through interaction with an Argonaute protein family member. While some members of this protein family retain an enzymatic activity capable of cleaving RNA molecules complementary to Argonaute-bound small RNAs, the role of the slicing activity in the canonical microRNA pathway is still unclear in animals. To address the importance of slicing Argonautes in animals, we created

Identifiers

PMID36711744
PMCPMC9882343
OpenAlexW4317585583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.