Evidence map›Paper›PMID 36711662›Full record

ArticlebioRxiv : the preprint server for biology2023

Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia.

Brennan P Bergeron, Kelly R Barnett, Kashi Raj Bhattarai, Robert J Mobley, Baranda S Hansen, Anthony Brown, Kiran Kodali, Anthony A High, Sima Jeha, Ching-Hon Pui and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Brennan P Bergeron
Kelly R Barnett
Kashi Raj Bhattarai
Robert J MobleyORCID 0000-0002-2728-8206
Baranda S Hansen
Anthony Brown
Kiran Kodali
Anthony A High
Sima Jeha
Ching-Hon Pui
Junmin Peng
Shondra M Pruett-Miller
Daniel Savic
St. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Characterizing noncoding GWAS variants in acute lymphoblastic leukemia treatment outcomeR01CA234490 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SAVIC, DANIEL · 2019 to 2023
$2.4M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA234490
6 · The paper itself

Abstract

Glucocorticoids (GCs; i.e., steroids) are important chemotherapeutic agents in the treatment of B-cell precursor acute lymphoblastic leukemia (B-ALL) and

Identifiers

PMID36711662
PMCPMC9882342
OpenAlexW4317653934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.