Evidence map›Paper›PMID 36711612›Full record

ArticlebioRxiv : the preprint server for biology2023

Active Gαi/o mutants accelerate breast tumor metastasis via the c-Src pathway.

Cancan Lyu, Aarzoo K Bhimani, William T Draus, Ronald Weigel, Songhai Chen

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cancan LyuThe Department of Neuroscience and Pharmacology, University of Iowa.
Aarzoo K BhimaniThe Department of Neuroscience and Pharmacology, University of Iowa.
William T DrausThe Department of Neuroscience and Pharmacology, University of Iowa.
Ronald WeigelThe Department of Surgery, University of Iowa.
Songhai ChenThe Department of Neuroscience and Pharmacology, University of Iowa.
University of Iowa · US

Funding

Role of Gi/o-GPCR signaling in breast cancer progressionR01CA207889 · NCI · UNIVERSITY OF IOWA · PI CHEN, SONGHAI, WEIGEL, RONALD J · 2017 to 2021
$2.3M
IVIS Biolumenscence and Fluorescence Live Animal ImagingS10OD026835 · OD · UNIVERSITY OF IOWA · PI RICE, KEVIN G · 2019 to 2019
$257k
NCI NIH HHS R01 CA207889NIH HHS S10 OD026835
6 · The paper itself

Abstract

Constitutively active mutations in the Gα

Identifiers

PMID36711612
PMCPMC9882124
OpenAlexW4317438743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.