Evidence map›Paper›PMID 36711601›Full record

ArticlebioRxiv : the preprint server for biology2024

pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of

Hsiao-Lin V Wang, Jian-Feng Xiang, Chenyang Yuan, Austin M Veire, Tania F Gendron, Melissa E Murray, Malú G Tansey, Jian Hu, Marla Gearing, Jonathan D Glass and 3 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Hsiao-Lin V WangDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-1889-4239
Jian-Feng XiangDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0001-5181-1645
Chenyang YuanDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.
Austin M VeireDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL 32224.ORCID 0000-0001-9327-0103
Tania F GendronDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL 32224.ORCID 0000-0002-7335-2627
Melissa E MurrayDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL 32224.
Malú G TanseyCenter for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL 32607.
Jian HuDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.
Marla GearingEmory Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-1959-7412
Jonathan D GlassEmory Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-3295-4971
Peng JinDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0001-6137-6659
Victor G CorcesDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0001-5140-4337
Zachary T McEachinDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-2369-8726
Emory University · USMayo Clinic in Florida · USUniversity of Florida · US

Funding

Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Dynamic DNA Modifications in Brain and DiseasesR35NS111602 · NINDS · EMORY UNIVERSITY · PI PENG JIN · 2019 to 2026
$6.5M
Dynamic RNA Modifications in human brain development and autismU01MH116441 · NIMH · EMORY UNIVERSITY · PI JIN, PENG · 2018 to 2022
$4.9M
Nuclear Organization and FunctionR35GM139408 · NIGMS · EMORY UNIVERSITY · PI CORCES, VICTOR G. · 2021 to 2025
$2.5M
Mechanisms of bisphenol A induced epigenomic alterations in the mammalian germlineF32ES031827 · NIEHS · EMORY UNIVERSITY · PI WANG, HSIAO-LIN V. · 2020 to 2022
$225k
NHGRI NIH HHS RM1 HG008935NIEHS NIH HHS F32 ES031827NIGMS NIH HHS R35 GM139408NIMH NIH HHS U01 MH116441NINDS NIH HHS R35 NS111602
6 · The paper itself

Abstract

Repeat expansions in the

Indexed as

Amyotrophic Lateral SclerosisChromatinEpigeneticsFrontotemporal DementiaNeurodegenerationsnATAC-seqsnRNA-seqTranscription

Identifiers

PMID36711601
PMCPMC9882184
OpenAlexW4316022484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.