Evidence map›Paper›PMID 36711538›Full record

ArticlebioRxiv : the preprint server for biology2023

Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System.

Jonathan Enders, Jarrid Jack, Sarah Thomas, Paige Lynch, Sarah Lasnier, Xin Cao, M Taylor Swanson, Janelle M Ryals, John P Thyfault, Patrycja Puchalska and 2 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jonathan EndersDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Jarrid JackDepartments of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Sarah ThomasDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Paige LynchDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Sarah LasnierDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Xin CaoDepartments of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS, 66160.
M Taylor SwansonDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Janelle M RyalsDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
John P ThyfaultDepartments of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS, 66160.
Patrycja PuchalskaDepartment of Medicine, Division of Molecular Medicine, University of Minnesota, Minneapolis, MN, 55455.
Peter A CrawfordDepartment of Medicine, Division of Molecular Medicine, University of Minnesota, Minneapolis, MN, 55455.
Douglas E WrightDepartments of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, 66160.
University of Kansas Medical Center · USUniversity of Minnesota · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Painful Versus Insensate Diabetic NeuropathyR01NS043314 · NINDS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2003 to 2026
$6.7M
KETONE BODY METABOLISM AND INTEGRATED METABOLIC HOMEOSTASISR01DK091538 · NIDDK · WASHINGTON UNIVERSITY · PI CRAWFORD, PETER A · 2011 to 2024
$6.2M
Kansas University Training Program in Neurological and Rehabilitation SciencesT32HD057850 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jacob J. Sosnoff · 2009 to 2026
$3.4M
Ketogenic Oscillations and Neurometabolic HealthspanR01AG069781 · NIA · UNIVERSITY OF MINNESOTA · PI CRAWFORD, PETER A, THYFAULT, JOHN P · 2020 to 2024
$2.3M
Translating Obesity, Metabolic Dysfunction and Comorbid Disease StatesT32DK128770 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI John P Thyfault, Douglas E Wright · 2022 to 2026
$806k
NIA NIH HHS R01 AG069781NICHD NIH HHS T32 HD057850NIDDK NIH HHS R01 DK091538NIDDK NIH HHS T32 DK128770NIGMS NIH HHS P20 GM103418NINDS NIH HHS R01 NS043314
6 · The paper itself

Abstract

Ketogenic diets are emerging as protective interventions in preclinical and clinical models of somatosensory nervous system disorders. Additionally, dysregulation of succinyl-CoA 3-oxoacid CoA-transferase 1 (SCOT, encoded by

Identifiers

PMID36711538
PMCPMC9882096
OpenAlexW4315929296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.