ArticleFrontiers in public health2022
Projecting the chronic disease burden among the adult population in the United States using a multi-state population model.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
108 citing papers in PubMed, 6 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- The effectiveness of alternatives to residential care for older people with on-going health and social care needs: a systematic review.BMC geriatrics · 2026Pooled it
- Nurse-led remote digital support for adults with chronic conditions: A systematic synthesis without meta-analysis.Journal of clinical nursing · 2025Pooled it
- Update on the Efficacy and Safety of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Chronic Diseases: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Familial resemblance in dietary intake among singletons, twins, and spouses: a meta-analysis of family-based observations.BMC public health · 2024Pooled it
- Total energy expenditure measured using doubly labeled water in adults with major chronic diseases: a systematic review.The American journal of clinical nutrition · 2024Pooled it
- Guideline
- A combined MeDi-DASH-CHH dietary intervention improves lipid profiles and enhances dietary adherence in northern Chinese older adults with dyslipidemia: A randomized controlled trial.European journal of clinical nutrition · 2026Trial
- Noninferior Immunogenicity and Consistent Safety of Respiratory Syncytial Virus Prefusion F Protein Vaccine in Adults 50-59 Years Compared to ≥60 Years of Age.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Trial
- Moving Person-Centered Care Planning From Theory Into Practice: Patient Perspectives.Learning health systems · 2026Article
- One-year mortality and functional outcome of inpatients aged 85 and older with thoracolumbar vertebral fractures: differences between operative and conservative treatment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Determining the age cut-off for increased surgical risk after Roux-en-Y gastric bypass in elderly patients: MBSAQIP 2015-2023 database analysis.Surgical endoscopy · 2026Article
- Postpandemic Telehealth Use: Patterns and Barriers for Older Adults in the United States, 2024.American journal of public health · 2026Article
- Impact of Social Support Networks on Job Satisfaction, Burnout, and Turnover Intentions in Primary Care Teams.Journal of general internal medicine · 2026Article
- Frailty in rheumatoid arthritis and the general population: a cross-sectional analysis of the Groningen Frailty Indicator and Fried criteria.Rheumatology (Oxford, England) · 2026Article
- Public Perception of Lifestyle Medicine and the Integration of Behavioral Health: A Nationally Representative Survey of U.S. Adults 18.American journal of lifestyle medicine · 2026Article
- Contribution of fungal diseases to the U.S. chronic disease burden.Clinical microbiology reviews · 2026Review
- Impact of Preoperative Osteoporotic Medications on Total Hip Arthroplasty Outcomes.Arthroplasty today · 2026Article
- Promoting the Concept Healthy Ageing for Use in Gerontological Health and Social Care Policy and Practice.Journal of clinical nursing · 2026Review
- Changes in working hours and burnout levels among physicians: a cohort study.Human resources for health · 2026Article
- Longitudinal associations between fast food outlet count and inflammatory markers in the US-based nurses' health study II between 1998 and 2011.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2026Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: As the United States population ages, the adult population with chronic diseases is expected to increase. Exploring credible, evidence-based projections of the future burden of chronic diseases is fundamental to understanding the likely impact of established and emerging interventions on the incidence and prevalence of chronic disease. Projections of chronic disease often involve cross-sectional data that fails to account for the transition of individuals across different health states. Thus, this research aims to address this gap by projecting the number of adult Americans with chronic disease based on empirically estimated age, gender, and race-specific transition rates across predetermined health states. Methods: We developed a multi-state population model that disaggregates the adult population in the United States into three health states, i.e., (a) healthy, (b) one chronic condition, and (c) multimorbidity. Data from the 1998 to 2018 Health and Retirement Study was used to estimate age, gender, and race-specific transition rates across the three health states, as input to the multi-state population model to project future chronic disease burden. Results: The number of people in the United States aged 50 years and older will increase by 61.11% from 137.25 million in 2020 to 221.13 million in 2050. Of the population 50 years and older, the number with at least one chronic disease is estimated to increase by 99.5% from 71.522 million in 2020 to 142.66 million by 2050. At the same time, those with multimorbidity are projected to increase 91.16% from 7.8304 million in 2020 to 14.968 million in 2050. By race by 2050, 64.6% of non-Hispanic whites will likely have one or more chronic conditions, while for non-Hispanic black, 61.47%, and Hispanic and other races 64.5%. Conclusion: The evidence-based projections provide the foundation for policymakers to explore the impact of interventions on targeted population groups and plan for the health workforce required to provide adequate care for current and future individuals with chronic diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.