Evidence map›Paper›PMID 36711243›Full record

ArticleiScience2023

Shenhe Liu, Xiaoya Ma, Zichen Wang, Feng Lin, Ming Li, Yali Li, Liu Yang, Hossam E Rushdi, Hasan Riaz, Tengyun Gao and 3 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. NSUN7 is a catalytically inactive RNA mNature communications · 2025
    Article
  5. Article
  6. Article
  7. NXPH4 mediated by mCellular & molecular biology letters · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Shenhe LiuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Xiaoya MaGuangxi Provincial Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China.
Zichen WangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Feng LinCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Ming LiCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Yali LiWuhan Benagen Technology Co, Ltd, Wuhan 430000, China.
Liu YangWuhan Benagen Technology Co, Ltd, Wuhan 430000, China.
Hossam E RushdiDepartment of Animal Production, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.
Hasan RiazDepartment of Biosciences, COMSATS University Islamabad, Sahiwal Campus, Punjab, Pakistan.
Tengyun GaoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Liguo YangChina Ministry of Education, Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
Tong FuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Tingxian DengGuangxi Provincial Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China.
Henan Agricultural University · CNGuangxi Buffalo Research Institute · CNHuazhong Agricultural University · CNCairo University · EGCOMSATS University Islamabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge of RNA molecules regulating testicular development and spermatogenesis in bulls is essential for elite bull selection and an ideal breeding program. Herein, we performed direct RNA sequencing (DRS) to explore the functional characterization of RNA molecules produced in the testicles of 9 healthy Simmental bulls at three testicular development stages (prepuberty, puberty, and postpuberty). We identified 5,043 differentially expressed genes associated with testicular weight. These genes exhibited more alternative splicing at sexual maturity, particularly alternative 3' (A3) and 5' (A5) splice sites usage and exon skipping (SE). The expression of hub genes in testicular developmental stages was also affected by both m6A and m5C RNA modifications. We found m5C-mediated splicing events significantly (p < 0.05) increased

Indexed as

AnimalsDevelopmental geneticsTranscriptomics

Identifiers

PMID36711243
PMCPMC9876746
OpenAlexW4313650707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.