ArticleFrontiers in aging neuroscience2022
Spontaneous brain activity in healthy aging: An overview through fluctuations and regional homogeneity.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- The lifespan trajectories of brain activities related to conflict-driven cognitive control.Science bulletin · 2025Pooled it
- The clinical relevance of healthy neurodevelopmental connectivity in childhood and adolescence: a meta-analysis of resting-state fMRI.Frontiers in neuroscience · 2025Pooled it
- Revisiting Amplitude of Low-Frequency Fluctuations (ALFF) in Resting-State fMRI: Clarifications and Improvements.Human brain mapping · 2026Article
- Distributed fMRI Patterns Coupled to Low-Frequency Cardiorespiratory Dynamics Provide Markers of Aging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Aperiodic parameters of the fMRI power spectrum associate with preterm birth and neonatal age.Communications biology · 2026Article
- Social mind at rest: resting-state connectivity associated with social thought relates to friendship quality.Social cognitive and affective neuroscience · 2026Article
- Distributed fMRI patterns coupled to low-frequency cardiorespiratory dynamics provide markers of aging.bioRxiv : the preprint server for biology · 2025Article
- Fractal Analysis of Brain Activity During Risky Drinking in Adolescents and Young Adults.Brain sciences · 2025Article
- Hidden Rhythms of a Developing Brain: Multimetric rs-fMRI Insights Into Typical Youth Maturation.Human brain mapping · 2025Article
- Assessment of alterations in regional homogeneity and amplitude of low-frequency fluctuations in children with dyslexia.Turkish journal of medical sciences · 2025Article
- Functional correlation tensors in brain white matter and the effects of normal aging.Brain imaging and behavior · 2024Article
- Fractional amplitude of low-frequency fluctuations during music-evoked autobiographical memories in neurotypical older adults.Frontiers in neuroscience · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study aims to explore whole-brain resting-state spontaneous brain activity using fractional amplitude of low-frequency fluctuation (fALFF) and regional homogeneity (ReHo) strategies to find differences among age groups within a population ranging from middle age to older adults. Methods: The sample comprised 112 healthy persons ( Results: Increased activity was found using fALFF in the superior temporal gyrus and inferior frontal gyrus when comparing the first group and the fifth. Regarding ReHo analysis, Group 6 showed increased ReHo in the temporal lobe (hippocampus), right and left precuneus, right caudate, and right and left thalamus depending on the age group. Moreover, significant correlations between age and fALFF and ReHo clusters, as well as with their gray matter volume were found, meaning that the higher the age, the higher the regional synchronization, the lower the fALFF activation, and the lower gray matter of the right thalamus. Conclusion: Both techniques have been shown to be valuable and usable tools for disentangling brain changes in activation in a very low interval of years in healthy aging.
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Registered trials
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