Evidence map›Paper›PMID 36711188›Full record

Trial reportOccupational therapy international2023

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial.

Anke P M Verhaegh, Brenda E Groen, Pauline B M Aarts, Raymond van Ee, Michèl A A P Willemsen, Marijtje L A Jongsma, Maria W G Nijhuis-van der Sanden

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Occupational therapy international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05533476 (Multi Sensory Stimulation And Priming), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05533476 nacompletednot on this map

Multi Sensory Stimulation And Priming (MuSSAP) in Infants (4-12 Months of Age) at Risk of Developing Unilateral Cerebral Palsy (uCP)

TypeinterventionalSponsorSint MaartenskliniekRan2016 to 2018Enrolled24ConditionsUnilateral Cerebral PalsyArmsMulti Sensory Stimulation and Priming, Intensive Usual Care (Upper Limb)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anke P M VerhaeghDepartment of Pediatric Rehabilitation, Sint Maartenskliniek, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-3983-4769
Brenda E GroenDepartment of Research and Innovation, Sint Maartenskliniek, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-8127-3857
Pauline B M AartsDepartment of Pediatric Rehabilitation, Sint Maartenskliniek, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-3603-4715
Raymond van EeDepartment of BioPhysics, Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-1134-8665
Michèl A A P WillemsenDepartment of Pediatric Neurology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0001-7860-7791
Marijtje L A JongsmaBehavioural Science Institute, Radboud University Nijmegen, Netherlands.ORCID https://orcid.org/0000-0001-7085-7497
Maria W G Nijhuis-van der SandenResearch Institute for Health Sciences, IQ healthcare, Radboud university medical center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-2637-6877
Radboud University Nijmegen · NLSint Maartenskliniek · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To explore the effect of an Early Intensive-Upper Limb intervention (EI-UL) compared to EI-UL with integrated Multisensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants with a unilateral brain lesion. Method: A pilot randomised clinical trial with pre- and postintervention and follow-up measurements (T0, T1, and T2) was conducted. Sixteen infants with a unilateral brain lesion (corrected age is 4-10 months) received home-based intervention with video coaching. Eight infants received EI-UL and eight infants received EI-UL with integrated MuSSAP training. Primary outcome was the Hand Assessment for Infants (HAI) score. Additionally, effects were explored on initiation of goal-directed movements in both groups and on attention in the EI-UL with integrated MuSSAP training group. Results: No significant group differences in HAI scores were found. Overall, HAI 'Affected hand score' increased between T0 and T1 ( Conclusion: The results suggest manual ability of infants with unilateral brain lesion improved with both interventions. We hypothesize that the integrated MuSSAP training may facilitate attention and initiation of contralesional upper limb goal-directed movements. This trial is registered with NCT05533476).

Indexed as

Occupational TherapyBrainHandHumansInfantPilot ProjectsUpper Extremity

Identifiers

PMID36711188
PMCPMC9839410
OpenAlexW4313612031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.