ArticleBiomedical engineering letters2023
Homodyne time-of-flight acousto-optic imaging for low-gain photodetector.
Article in Biomedical engineering letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Acousto-Optics: Recent Studies and Medical Applications.Biosensors · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acousto-optics imaging (AOI) is a hybrid imaging modality that is capable of mapping the light fluence rate in deep tissue by local ultrasound modulation of the diffused photons. Since the intensity of the modulated photons is relatively low, AOI systems often rely on high-gain photodetectors, e.g. photomultiplier tubes (PMTs), which limit scalability due to size and cost and may significantly increase the relative shot-noise in the detected signal due to low quantum yields or gain noise. In this work, we have developed a homodyne AOI scheme in which the modulated photons are amplified by interference with a reference beam, enabling their detection with a single low-gain photodetector in reflection-mode configuration. We experimentally demonstrate our approach with a silicon photodiode, achieving over a 4-fold improvement in SNR in comparison to a PMT-based setup. The increased SNR manifested in lower background noise level thus enabling deeper imaging depths. The use of a fiber-based configuration enables the integration of our scheme in a hand-held AOI probe.
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