Evidence map›Paper›PMID 36710924›Full record

ArticleCanadian respiratory journal2023

Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis.

Udari Eshani Perera, Louise Organ, Simon G Royce, Chrishan S Samuel, Habtamu B Derseh, Sasika N V Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J Snibson

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Udari Eshani PereraSchool of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-3381-9165
Louise OrganNottingham Respiratory Research Unit, University of Nottingham, Nottingham, UK.ORCID 0000-0002-1665-395X
Simon G RoyceCardiovascular Disease Program, Monash Biomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-5841-1775
Chrishan S SamuelCardiovascular Disease Program, Monash Biomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, Victoria, Australia.ORCID 0000-0003-0295-4214
Habtamu B DersehSchool of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-3415-7968
Sasika N V DewageWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0002-1259-2926
Emmanuel KoumoundourosDepartment of Electrical and Electronic Engineering, The University of Melbourne, Parkville, VIC, Australia.
Andrew StentSchool of Veterinary Science, The University of Melbourne, Werribee, VIC, Australia.ORCID 0000-0002-4432-8185
Kenneth J SnibsonSchool of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0003-4772-9408
The University of Melbourne · AUAustralian Regenerative Medicine Institute · AUUniversity of Nottingham · GBWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by excessive deposition of extracellular matrix in the interstitial lung parenchyma, often manifested by dyspnea and progressive loss of lung function. The role of inflammation in the pathogenesis of IPF is not well understood. This study evaluated the histopathological and inflammatory components of bleomycin-induced pulmonary fibrosis in mouse and sheep models, in terms of their ability to translate to the human IPF. Merino sheep (

Indexed as

BleomycinIdiopathic Pulmonary FibrosisAnimalsDisease Models, AnimalHumansInflammationLungMiceBleomycin

Identifiers

PMID36710924
PMCPMC9876680
OpenAlexW4317213337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.