Evidence map›Paper›PMID 36710876›Full record

ArticleFrontiers in molecular biosciences2022

Transcription factor Ap2b regulates the mouse autosomal recessive polycystic kidney disease genes,

Maoqing Wu, Naoe Harafuji, Amber K O'Connor, Ljubica Caldovic, Lisa M Guay-Woodford

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Side-Chain Homologs of ΔMolecular neurobiology · 2026
    Article
  2. Article
  3. Article
  4. Studies of mice with a large deletion of the ARPKD-associatedbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maoqing WuCenter for Translational Research, Children's National Hospital, Washington, DC, United States.
Naoe HarafujiCenter for Translational Research, Children's National Hospital, Washington, DC, United States.
Amber K O'ConnorO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Ljubica CaldovicCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC, United States.
Lisa M Guay-WoodfordCenter for Translational Research, Children's National Hospital, Washington, DC, United States.
Children's National · USUniversity of Alabama at Birmingham · US

Funding

Decoding reno-protective mechanisms in mouse Pkhd1 models: Implications for ARPKD therapeuticsR01DK121530 · NIDDK · CHILDREN'S RESEARCH INSTITUTE · PI CALDOVIC, LJUBICA MORIZONO, GUAY-WOODFORD, LISA MARIE · 2020 to 2024
$1.9M
NIDDK NIH HHS R01 DK121530
6 · The paper itself

Abstract

Transcription factor Ap2b (TFAP2B), an AP-2 family transcription factor, binds to the palindromic consensus DNA sequence, 5'-GCCN

Indexed as

autosomal recessive polycystic kidney disease (ARPKD)Cys1Pkhd1Tfap2bTFAP2B

Identifiers

PMID36710876
PMCPMC9877354
OpenAlexW4315782241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.