Evidence map›Paper›PMID 36710637›Full record

ArticleBMJ open ophthalmology2022

Heavy silicone oil tamponade: a multicentre experience.

Max Davidson, Samir Dowlut, Jufen Zhang, Khayam Naderi, Teresa Sandinha, Megan Kay Wood, Matthew Schneiders, Shohista Saidkasimova, Shamfa Peart, Ray Chaudhuri and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. One-Month versus 3-Month Heavy Silicone Oil Tamponade in Complex Rhegmatogenous Retinal Redetachment.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2026
    Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 2 countries.

Max DavidsonSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK max.davidson@hotmail.co.uk.ORCID 0000-0002-3895-3953
Samir DowlutSouthend University Hospital, Southend, UK.
Jufen ZhangAnglia Ruskin University, Cambridge, UK.
Khayam NaderiSouthend University Hospital, Southend, UK.
Teresa SandinhaSt Paul's Eye Hospital, Liverpool, UK.
Megan Kay WoodAlder Hey Children's NHS Foundation Trust, Liverpool, UK.ORCID 0000-0003-1975-477X
Matthew SchneidersNorfolk & Norwich University Hospitals NHS Foundation Trust, Norfolk, UK.
Shohista SaidkasimovaGartnavel General Hospital, Glasgow, UK.
Shamfa PeartLeicester Royal Infirmary, Leicester, UK.
Ray ChaudhuriLeicester Royal Infirmary, Leicester, UK.
Manish GundaQueen Elizabeth Hospital, King's Lynn, UK.
Manzar SaeedQueen Elizabeth Hospital, King's Lynn, UK.
Florian HeussenUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Johannes KellerUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Sonali TarafdarNinewells Hospital, Dundee, UK.
Aman ChandraSouthend University Hospital, Southend, UK.
Southend University Hospital NHS Foundation Trust · GBLeicester Royal Infirmary · GBQueen Elizabeth Hospital King's Lynn NHS Foundation Trust · GBUniversity Hospitals Bristol NHS Foundation Trust · GBAlder Hey Children's NHS Foundation Trust · GBAnglia Ruskin University · GBGartnavel General Hospital · GBHe Eye Hospital · CNNinewells Hospital · GBNorfolk and Norwich University Hospitals NHS Foundation Trust · GBSheffield Teaching Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications. METHODS AND ANALYSIS: Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil.

results134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes).

conclusionThis is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

Indexed as

Retinal DetachmentHumansSilicone OilsTreatment OutcomeVitrectomydensironSilicone Oilsretinatreatment surgery

Identifiers

PMID36710637
PMCPMC9743375
OpenAlexW4310905061

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.