Evidence map›Paper›PMID 36710073›Full record

ArticleJournal of geriatric psychiatry and neurology2023

Regional Vulnerability of the Corpus Callosum in the Context of Cardiovascular Risk.

Anna M VandeBunte, Corrina Fonseca, Emily W Paolillo, Eva Gontrum, Shannon Y Lee, Joel H Kramer, Kaitlin B Casaletto

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric psychiatry and neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Metabolic, demographic, and behavioral risk factors predict brain structural variability in the general population: an analysis of the human connectome project young adults.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  9. Vascular risk, gait, behavioral, and plasma indicators of VCID.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna M VandeBunteDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.ORCID 0000-0002-5167-3358
Corrina FonsecaDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
Emily W PaolilloDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
Eva GontrumDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
Shannon Y LeeDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
Joel H KramerDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
Kaitlin B CasalettoDepartment of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, CA, USA.
University of California, San Francisco · USPalo Alto University · US

Funding

Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Gil Dan Rabinovici · 2019 to 2026
$36.9M
Mechanisms of Executive Decline in Normal AgingR01AG032289 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kaitlin B Casaletto, JOEL H KRAMER · 2009 to 2026
$8.3M
Biological Predictors Of Brain Aging Trajectories Diversity Supplement: African American Outreach And The Intersection Between Social Determinants Of Health And Biomarkers Of Degenerative DiseaseRF1AG032289 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRAMER, JOEL H · 2020 to 2021
$5.3M
Unraveling the intersection of synaptic biology, lifestyle, and cognitive resilienceR01AG072475 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CASALETTO, KAITLIN B · 2021 to 2025
$4.3M
Can Behavior Shape Neural Health? Identifying Modifiable Factors to Prevent Cognitive Decline in AgeK23AG058752 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CASALETTO, KAITLIN B · 2018 to 2022
$994k
NIA NIH HHS K23 AG058752NIA NIH HHS P30 AG062422NIA NIH HHS R01 AG032289NIA NIH HHS R01 AG072475NIA NIH HHS RF1 AG032289
6 · The paper itself

Abstract

Many factors outside of cardiovascular health can impact the structure of white matter. Identification of reliable and clinically meaningful biomarkers of the neural effects of systemic and cardiovascular health are needed to refine etiologic predictions. We examined whether the corpus callosum demonstrates regional vulnerability to systemic cardiovascular risk factors. Three hundred and ninety-four older adults without dementia completed brain MRI, neurobehavioral evaluations, and blood draws. A subset (

Indexed as

Cardiovascular DiseasesCorpus CallosumAgedBrainDiffusion Tensor ImagingHeart Disease Risk FactorsHumansInterleukin-6Risk FactorsInterleukin-6blood glucoseblood pressurecerebrovascularcognitive agingdiffusion tensor imaginginflammatory markers

Identifiers

PMID36710073
PMCPMC10441555
OpenAlexW4318542367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.