Evidence map›Paper›PMID 36709657›Full record

Trial reportValue in health regional issues2023

Cost of Home-Based Couples Human Immunodeficiency Virus Counseling and Testing and Human Immunodeficiency Virus Self-Testing During Pregnancy and Postpartum in Southwestern Kenya.

Seth J Borgstede, Assurah Elly, Anna Helova, Zachary Kwena, Lynae A Darbes, Abigail Hatcher, Harsha Thirumurthy, George Owino, Maria Pisu, Kevin Owuor and 4 more

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Value in health regional issues, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03547739 (Testing Strategies for Couple Engagement in PMTCT and Family Health in Kenya), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03547739 nacompletednot on this map

Testing Strategies for Couple Engagement in PMTCT and Family Health in Kenya

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2019 to 2024Enrolled1,600ConditionsHuman Immunodeficiency VirusArmsHome visits, HIV Self-testing
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Seth J BorgstedeDepartment of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Assurah EllyResearch, Care and Treatment Programme, Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Anna HelovaDepartment of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA; Sparkman Center for Global Health, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Zachary KwenaResearch, Care and Treatment Programme, Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lynae A DarbesCenter for Sexuality and Health Disparities, and Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA.
Abigail HatcherDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Harsha ThirumurthyDepartment of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
George OwinoResearch, Care and Treatment Programme, Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Maria PisuDepartment of Preventive Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Kevin OwuorDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Thomas BraunDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Janet M TuranDepartment of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA; Sparkman Center for Global Health, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Elizabeth A BukusiResearch, Care and Treatment Programme, Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Van T NghiemDepartment of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: nghiem@uab.edu.
Kenya Medical Research Institute · KEAlabama Department of Public Health · USUniversity of Alabama at Birmingham · USUniversity of Michigan · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
Testing Strategies for Couple Engagement in PMTCT and Family Health in KenyaR01MH116736 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DARBES, LYNAE A, TURAN, JANET M. · 2018 to 2023
$3.1M
NIAID NIH HHS P30 AI027767NIMH NIH HHS R01 MH116736
6 · The paper itself

Abstract

objectiveHome-based couples HIV testing and counseling and HIV self-testing (HIVST) for pregnant women can promote HIV status disclosure and male partner testing; however, cost data are lacking. We examined a home-based couples intervention (HBCI) and HIVST intervention costs per couple (unit cost) during pregnancy and postpartum in Kenya.

methodsThis randomized controlled trial is comparing HBCI and HIVST for couples among pregnant women attending antenatal care clinics in two counties in southwestern Kenya. We used micro-costing to estimate the unit cost per couple receiving the intervention as the total of direct and indirect costs for each study arm in 2019 US$. We used a one-month window to conduct a time and motion study to determine personnel effort and resources. We then compared the unit cost by arm, identified key cost drivers, and conducted sensitivity analyses for cost uncertainties.

resultsAt base-case, the unit cost was $129.01 and $41.99, respectively, for HBCI and HIVST. Personnel comprised half of the unit cost for both arms. Staff spent more time on activities related to participant engagement in HBCI (accounting for 6.4% of the unit cost) than in HIVST (2.3%). Staff training was another key cost driver in HBCI (20.1% of the unit cost compared to 12.5% in HIVST). Sensitivity analyses revealed that the unit cost ranges were $104.64-$154.54 for HBCI and $30.49-$56.59 for HIVST.

conclusionsOur findings may guide spending decisions for future HIV prevention and treatment programs for pregnant couples in resource-limited settings such as Kenya.

Indexed as

HIV InfectionsSelf-TestingCounselingFemaleHIVHIV TestingHumansKenyaMalePostpartum PeriodPregnancycostscounselingcouples therapyHIVHIV testinghome care servicesKenyamother-to-child transmissionself-testing

Identifiers

PMID36709657
PMCPMC9992305
OpenAlexW4318305265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.