Evidence map›Paper›PMID 36709386›Full record

Observational studyPediatric research2023

Impaired aerobic capacity in adolescents and young adults after treatment for cancer or non-malignant haematological disease.

Arthur Gavotto, Vincent Dubard, Martina Avesani, Helena Huguet, Marie-Christine Picot, Hamouda Abassi, Sophie Guillaumont, Gregoire De La Villeon, Stephanie Haouy, Nicolas Sirvent and 5 more

2 registry-linked trialsOpen access · greenAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04815447 completednot on this map

Cardiopulmonary Fitness and Its Clinical Determinants of a Population of Childhood Cancer Survivor: a Controlled Retrospective Study

TypeobservationalSponsorUniversity Hospital, MontpellierRan2020 to 2021Enrolled500ConditionsChildhood Cancer
NCT07728435 completednot on this mapstarted 2025, after this paper: background citation

Cardiopulmonary Fitness and Health-Related Quality of Life in Children and Adolescents With Type 1 Diabetes: The Prospective Multicenter Controlled FIT-T1D Study

TypeobservationalSponsorInstitut Saint PierreRan2025 to 2026Enrolled214ConditionsDiabete Type 1
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Early and Stage-Dependent Cardiopulmonary Fitness Impairment in Pediatric CKD.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Arthur GavottoPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Vincent DubardPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Martina AvesaniPaediatric and Congenital Cardiology Department, M3C National Reference Centre, Bordeaux University Hospital, Bordeaux, France.
Helena HuguetEpidemiology and Clinical Research Department, Clinical Investigation Centre, INSERM-CIC 1411, University of Montpellier, Montpellier University Hospital, Montpellier, France.
Marie-Christine PicotEpidemiology and Clinical Research Department, Clinical Investigation Centre, INSERM-CIC 1411, University of Montpellier, Montpellier University Hospital, Montpellier, France.
Hamouda AbassiPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Sophie GuillaumontPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Gregoire De La VilleonPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Stephanie HaouyPaediatric Cancer Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Nicolas SirventPaediatric Cancer Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Anne SirventPaediatric Cancer Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Alexandre TheronPaediatric Cancer Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Anne RequirandPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Stefan MateckiPaediatric Cardiology and Pulmonology Unit, Department of Paediatrics, Montpellier University Hospital, Montpellier, France.
Pascal AmedroPaediatric and Congenital Cardiology Department, M3C National Reference Centre, Bordeaux University Hospital, Bordeaux, France. pascal.amedro@chu-bordeaux.fr.
Université de Montpellier · FRCentre Hospitalier Universitaire de Montpellier · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChildhood cancer survivors are at increased risk for cardiovascular disease. Maximal oxygen uptake (VO

methodThis is a controlled cross-sectional study.

resultsA total of 477 subjects (77 in remission and 400 controls), aged from 6 to 25 years, were included, with a mean delay between end of treatment and CPET of 2.9 ± 2.3 years in the remission group. In this group, the mean VO

conclusionImpaired aerobic capacity had a higher prevalence in adolescents and young adults in cancer remission. This impairment was primarily related to physical deconditioning and not to heart failure. TRIAL REGISTRY: NCT04815447. IMPACT: In childhood cancer survivors, aerobic capacity is five times more impaired than in healthy subjects. This impairment mostly reflects early onset of physical deconditioning. No evidence of heart failure was observed in this population.

Indexed as

Cancer SurvivorsHeart FailureHematologic DiseasesNeoplasmsAdolescentAdultChildCross-Sectional StudiesExercise TestFemaleHumansMaleOxygen ConsumptionYoung Adult

Identifiers

PMID36709386
OpenAlexW4318332925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.