Evidence map›Paper›PMID 36709341›Full record

ArticleScientific reports2023

CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion.

Yu-Cheng Yao, Hsien Chao, Kun-Yu Kao, Hsi-Hsien Lin, Shih-Tien Wang, Ming-Chau Chang, Chien-Lin Liu, Po-Hsin Chou

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Generation and validation of a Hounsfield unit (HU) threshold for predicting mechanical and junctional complications following thoracolumbar or lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
  2. Pooled it
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  4. Multifactorial prediction of mechanical complications after lumbar fusion using bone quality and turnover markers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Multimodal model predicts screw loosening at user-specified postoperative time points after single-level lumbar interbody fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  7. The HBA-3 score: a simple bedside tool to predict cage subsidence after TLIF.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  8. Bone density-optimized pedicle screw planning enhances mechanical stability.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  10. Osteoporosis prediction using lumbar CT Hounsfield units: comparative performance and clinical implications of seven machine learning models.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  11. Local fragility index and Radiomics-lite modeling of CT-Derived Hounsfield units for osteoporosis risk assessment in spine surgery patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  16. Endplate Hounsfield units outperform lumbar HU and VBQ in predicting cage subsidence after posterior lumbar interbody fusion: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  17. Hounsfield units vs. vertebral bone quality score: which is a better predictor of screw loosening after single-level lumbar interbody fusion?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Cheng YaoDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Hsien ChaoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Kun-Yu KaoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hsi-Hsien LinDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Shih-Tien WangDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Ming-Chau ChangDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chien-Lin LiuDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Po-Hsin ChouDepartment of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan. choupohsin@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrospective cohort study. To validate computed tomography (CT) radiodensity in Hounsfield units (HU) as a prognostic marker for pedicle screw loosening or cage subsidence in minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). The retrospective study involved 198 patients treated with MI-TLIF. Screw loosening (SL), cage subsidence (CS), and fusion status were assessed by plain radiographs. The risk factors of SL and CS were identified using logistic regression. A total of 258 levels and 930 screws were analyzed. During a 2-year follow-up, 16.2% and 24.7% of patients had CS and SL respectively. The cut-off value of L1 HU for predicting SL or CS was 117. The L1 HU < 117 and BMI ≥ 25 were two independent risk factors. The risk of SL or CS was 4.1 fold in patients L1 HU < 117 and 2.6 fold in patients with BMI ≥ 25. For patients concurrently having BMI ≥ 25 and pre-op L1 HU < 117, the risk was 4.3 fold. Fusion rate and clinical outcome were comparable in patients with SL or CS. L1 HU < 117 and BMI > 25 were two independent risk factors that can be screened preoperatively for preventing SL or CS and lead to better management of patients undergoing MI-TLIF.

Indexed as

Pedicle ScrewsSpinal FusionHumansLumbar VertebraeRetrospective StudiesTomography, X-Ray ComputedTreatment Outcome

Identifiers

PMID36709341
PMCPMC9884280

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.