Evidence map›Paper›PMID 36709233›Full record

ArticleAnnals of biomedical engineering2023

Prediction of Temperature and Loading History Dependent Lumbar Spine Biomechanics Under Cyclic Loading Using Recurrent Neural Networks.

Nadja Blomeyer, Saurabh Balkrishna Tandale, Luis Fernando Nicolini, Philipp Kobbe, Thomas Pufe, Bernd Markert, Marcus Stoffel

Abstract read
In one paragraph

Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nadja Blomeyer *Institute of General Mechanics, RWTH Aachen University, Eilfschornsteinstr. 18, 52062, Aachen, Germany. nadja.wilmanns@rwth-aachen.de.ORCID http://orcid.org/0000-0002-2092-517X
Saurabh Balkrishna Tandale *Institute of General Mechanics, RWTH Aachen University, Eilfschornsteinstr. 18, 52062, Aachen, Germany.
Luis Fernando NicoliniInstitute of General Mechanics, RWTH Aachen University, Eilfschornsteinstr. 18, 52062, Aachen, Germany.
Philipp KobbeDepartment of Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Thomas PufeDepartment of Anatomy and Cell Biology, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Bernd MarkertInstitute of General Mechanics, RWTH Aachen University, Eilfschornsteinstr. 18, 52062, Aachen, Germany.
Marcus StoffelInstitute of General Mechanics, RWTH Aachen University, Eilfschornsteinstr. 18, 52062, Aachen, Germany.

Funding

Bundesministerium für Bildung und Forschung WorkHealth
6 · The paper itself

Abstract

Extended-duration cyclic loading of the spine is known to be correlated to lower back pain (LBP). Therefore, it is important to understand how the loading history affects the entire structural behavior of the spine, including the viscoelastic effects. Six human spinal segments (L4L5) were loaded with pure moments up to 7.5 Nm cyclically for half an hour, kept unloaded for 15 min, and loaded with three cycles. This procedure was performed in flexion-extension (FE), axial rotation (AR), and lateral bending (LB) and repeated six times per direction for a total of 18 h of testing per segment. A Long Short-Term Memory (LSTM) Recurrent Neural Network (RNN) was trained to predict the change in the biomechanical response under cyclic loading. A strong positive correlation between the total testing time and the ratio of the third cycle to the last cycle of the loading sequence was found (BT: [Formula: see text] =  0.3469, p = 0.0003, RT: [Formula: see text] =0.1988, p  =   0.0377). The moment-range of motion (RoM) curves could be very well predicted with an RNN ([Formula: see text]=0.988), including the correlation between testing time and testing temperature as inputs. This study shows successfully the feasibility of using RNNs to predict changing moment-RoM curves under cyclic moment loading.

Indexed as

Lumbar VertebraeBiomechanical PhenomenaCadaverHumansRange of Motion, ArticularRotationTemperatureBiomechanicsLoading-historyRecurrent Neural NetworkSpineViscoelasticity

Identifiers

PMID36709233
PMCPMC10172265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.