Evidence map›Paper›PMID 36708849›Full record

ArticleActa biomaterialia2023

Numerical model characterization of the sound transmission mechanism in the tympanic membrane from a high-speed digital holographic experiment in transient regime.

J Garcia-Manrique, Cosme Furlong, A Gonzalez-Herrera, Jeffrey T Cheng

Open access · hybridAbstract read
In one paragraph

Article in Acta biomaterialia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

J Garcia-ManriqueDepartment of Civil Engineering, Materials and Manufacturing, School of Engineering, University of Malaga, Spain; Eaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, USA. Electronic address: josegmo@uma.es.
Cosme FurlongCenter for Holographic Studies and Laser micro-mechaTronics (CHSLT), Worcester, MA, USA; Mechanical Engineering Department, Worcester Polytechnic Institute, Worcester, MA, USA.
A Gonzalez-HerreraDepartment of Civil Engineering, Materials and Manufacturing, School of Engineering, University of Malaga, Spain.
Jeffrey T ChengEaton-Peabody Laboratory, Massachusetts Eye and Ear, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.
Massachusetts Eye and Ear Infirmary · USUniversidad de Málaga · ESWorcester Polytechnic Institute · US

Funding

Middle Ear Nonlinearity in High Intensity Sound: Impact on Hearing Damage and ProtectionR01DC016079 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Jeffrey Tao Cheng · 2017 to 2026
$4.1M
NIDCD NIH HHS R01 DC016079
6 · The paper itself

Abstract

A methodology for the development of a finite element numerical model of the tympanic membrane (TM) based on experiments carried out in the time domain on a cadaveric human temporal bone is presented. Using a high-speed digital holographic (HDH) system, acoustically-induced transient displacements of the TM surface are obtained. The procedure is capable to generate and validate the finite element model of the TM by numerical and experimental data correlation. Reverse engineering approach is used to identify key material parameters that define the mechanical response of the TM. Finally, modal numerical simulations of the specimen are performed. Results show the feasibility of the methodology to obtain an accurate model of a specific specimen and to help interpret its behaviour with additional numerical simulations. STATEMENT OF SIGNIFICANCE: Improving knowledge of the dynamic behavior of the tympanic membrane is key to understanding the sound transmission system in human hearing and advance in the treatment of its pathologies. Recently we acquired a new tool to carry out experiments in transient regime by means of digital laser holography, capable of providing a large amount of information in a controlled transient test. In this work, these data are used to develop a methodology that generates a numerical model of the tympanic membrane based on numerical-experimental correlations. It is important to be able to develop models that fit specific patients. In this work, additional modal simulations are also presented that, in addition to validating the results, provide more information on the specimen.

Indexed as

HolographyTympanic MembraneFinite Element AnalysisHumansSoundVibrationAcoustic–structural coupled analysisFinite element modelHigh-speed digital holographicSound transmissionTympanic membrane

Identifiers

PMID36708849
PMCPMC10193188
OpenAlexW4318450604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.