Evidence map›Paper›PMID 36708439›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2023

Performance of 8- vs 16 ECG-gated reconstructions in assessing myocardial function using Rubidium-82 myocardial perfusion imaging: Findings in a young, healthy population.

Martin Lyngby Lassen, Mads Wissenberg, Christina Byrne, Andreas Kjaer, Philip Hasbak

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Enhanced accuracy of cardiacEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Martin Lyngby LassenDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Section 4011, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark. martin.lyngby.lassen@regionh.dk.
Mads WissenbergDepartment of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Christina ByrneDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Section 4011, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Section 4011, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Philip HasbakDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Section 4011, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
University of Copenhagen · DKGentofte Hospital · DKRigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent imaging guidelines recommend using at least 16 ECG gates when performing MUGA and cardiac SPECT to assess left ventricular ejection fraction (LVEF). However, for Rubidium-82 (

methodsThe study comprised 25 healthy volunteers (median age 23 years) who underwent repeat MPI sessions employing

resultsSimilar LVEF and LVEF reserve estimates were found for the 8- and 16-gated reconstructions ([%] LVEF (8/16 gates): rest = 61 ± 6/64 ± 6, stress = 68 ± 7/71 ± 6, LVEF reserve (8/16 gates): 8 ± 3/6 ± 4, and all P ≥ 0.13). Similar test-retest repeatability measures were observed for rest and stress LVEF and their reserves [LVEF (8/16 gates); Rest = 4.5/4.6 (P = 0.81), Stress = 3.5/3.2 (P = 0.33), LVEF reserve = 46.7/49.3 (P = 0.13)].

conclusionIn healthy subjects, 8 and 16 ECG gates can be used interchangeably if only volumetric assessments are desired. However, if filling and emptying rates are of interest, a minimum of 16 ECG gates should be employed.

Indexed as

Myocardial Perfusion ImagingVentricular Function, LeftAdultElectrocardiographyHumansPerfusionPositron-Emission TomographyPositron Emission Tomography Computed TomographyRubidium RadioisotopesStroke VolumeYoung AdultRubidium-82Rubidium Radioisotopesadenosinecardiac imagingEjection fractionPET

Identifiers

PMID36708439
OpenAlexW4318346702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.