SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023
Factors influencing cage subsidence in anterior cervical corpectomy and discectomy: a systematic review.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 3D-printed porous titanium versus polyetheretherketone cages in lateral lumbar interbody fusion: a systematic review and meta-analysis of subsidence.Frontiers in medicine · 2024Pooled it
- Comparative analysis of novel vertebral bone quality score variants for predicting cage subsidence following single-level anterior cervical discectomy and fusion: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Is preoperative cervical range of motion associated with cage subsidence after anterior cervical discectomy and fusion?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Anterior Cervical Osteotomy: A Narrative Review and Proposal of a Mechanism-Based Decision Framework (The ACO Triad).Global spine journal · 2026Review
- Subchondral Bone Density Distribution in Canine C6-C7 Vertebral Endplates Affected by DA-CSM: A CT-OAM Study.Animals : an open access journal from MDPI · 2026Article
- Expandable corpectomy cage with articulating endcap for correction of severe cervical kyphotic deformity: a case report.Journal of spine surgery (Hong Kong) · 2026Article
- MRI-based endplate bone quality scoring system in cervical OPLL: a novel measuring method predicting titanium mesh cage subsidence following ACCF.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Predictive efficacy of phantom-less calibration of computed tomography for cage subsidence after anterior cervical discectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Article
- [Clinical efficacy of anterior cervical mortise-tenon corpectomy and fusion for the treatment of ossification of the posterior longitudinal ligament].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Influence of cage material, plating and vertebral bone quality on subsidence and long-term outcomes following anterior cervical discectomy and fusion-a retrospective analysis.Journal of spine surgery (Hong Kong) · 2026Article
- Comparing the Prognostic Utility of Vertebral and Endplate Bone Quality Scores for Cage Subsidence Following Single-Level Anterior Cervical Discectomy and Fusion: A Retrospective Analysis.Orthopaedic surgery · 2026Article
- Interbody cage subsidence after ACDF: a predictor of non-union and neck pain despite normal bone mineral density.Neurosurgical review · 2026Article
- A novel method of C-VBQ score and CT-HU as risk predictors for cage subsidence after short level ACDF.Scientific reports · 2026Article
- Development and validation of a nomogram prediction model for assessing cage subsidence risk following anterior cervical discectomy and fusion.BMC musculoskeletal disorders · 2026Article
- The number of fusion levels as a potential factor influencing long-term complications of anterior controllable antedisplacement fusion: a biomechanical analysis.Frontiers in surgery · 2026Article
- Deciphering subsidence risk after ACDF: a biomechanical study on bone density and endplate thickness.BMC musculoskeletal disorders · 2025Article
- Risk Factors for Poor Matching of Intervertebral Fusion Devices After Posterior Vertebral Column Resection in Patients With Kyphosis or Kyphoscoliosis.Orthopaedic surgery · 2025Article
- An innovative self-stabilised 3D-printed artificial vertebral body designed for clinical application and comparison with the conventional implants.Journal of orthopaedic translation · 2025Article
- Finite Element Analysis of Biomechanical Assessment: Traditional Bilateral Pedicle Screw System vs. Novel Reverse Transdiscal Screw System for Lumbar Degenerative Disc Disease.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVarious factors have been examined in relation to cage subsidence risk, including cage material, cage geometry, bone mineral density, device type, surgical level, bone graft, and patient age. The present study aims to compare and synthesize the literature of both clinical and biomechanical studies to evaluate and present the factors associated with cage subsidence.
methodsA comprehensive search of the literature from January 2003 to December 2021 was conducted using the PubMed and ScienceDirect databases by following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Following the screening for inclusion and exclusion criteria, a total of 49 clinical studies were included. Correlations between clinical and biomechanical studies are also discussed.
resultsPatients treated with the cage and plate combination had a lower subsidence rate than patients with the stand-alone cage. Overall, Polyetheretherketone material was shown to have a lower subsidence rate than titanium and other materials. The subsidence rate was also higher when the surgery was performed at levels C5-C7 than at levels C2-C5. No significant correlation was found between age and cage subsidence clinically.
conclusionsCage subsidence increases the stress on the anterior fixation system and may cause biomechanical instability. Severe cage subsidence decreases the Cobb angle and intervertebral height, which may cause destabilization of the implant system, such as screw/plate loosening or breakage of the screw/plate. Various factors have been shown to influence the risk of cage subsidence. Examining clinical research alongside biomechanical studies offers a more comprehensive understanding of the subject.
Indexed as
Identifiers
36708398What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.