Evidence map›Paper›PMID 36708390›Full record

ArticleArchives of microbiology2023

Environmental surveillance of SARS-CoV-2 in municipal wastewater to monitor COVID-19 status in urban clusters in Malaysia.

Muhamad Afiq Aziz, Syuhada Norman, Suzaini Mohamed Zaid, Khanom Simarani, Raha Sulaiman, Alijah Mohd Aris, Khor Bee Chin, Rozainanee Mohd Zain

Abstract read
In one paragraph

Article in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhamad Afiq Aziz *Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. afiqaziz@um.edu.my.ORCID http://orcid.org/0000-0001-5624-2218
Syuhada Norman *Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Suzaini Mohamed ZaidFaculty of Built Environment, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Khanom SimaraniInstitute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Raha SulaimanFaculty of Built Environment, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Alijah Mohd ArisIndah Water Konsortium Sdn Bhd, No. 44, Jalan Dungun, Damansara Heights, 50490, Kuala Lumpur, Malaysia.
Khor Bee ChinIndah Water Konsortium Sdn Bhd, No. 44, Jalan Dungun, Damansara Heights, 50490, Kuala Lumpur, Malaysia.
Rozainanee Mohd ZainVirology Unit, Institute for Medical Research, Infectious Disease Research Centre, National Institute of Health (NIH), Bandar Setia Alam, 40170, Shah Alam, Selangor, Malaysia.

Funding

Institut Pengurusan dan Pemantauan Penyelidikan, Universiti Malaya CSRG007-2020ST
6 · The paper itself

Abstract

Wastewater monitoring for SARS-CoV-2 has attracted considerable attention worldwide to complement the existing clinical-based surveillance system. In this study, we report our first successful attempt to prove the circulation of SARS-CoV-2 genes in Malaysian urban wastewater. A total of 18 wastewater samples were obtained from a regional sewage treatment plant that received municipal sewage between February 2021 and May 2021. Using the quantitative PCR assay targeting the E and RdRp genes of SARS-CoV-2, we confirmed that both genes were detected in the raw sewage, while no viral RNA was found in the treated sewage. We were also able to show that the trend of COVID-19 cases in Kuala Lumpur and Selangor was related to the changes in SARS-CoV-2 RNA levels in the wastewater samples. Overall, our study highlights that monitoring wastewater for SARS-CoV-2 should help local health professionals to obtain additional information on the rapid and silent circulation of infectious agents in communities at the regional level.

Indexed as

COVID-19Environmental MonitoringHumansMalaysiaRNA, ViralSARS-CoV-2SewageWastewaterRNA, ViralSewageWastewaterCOVID-19MalaysiaMunicipalSARS-CoV-2 RNAWastewater

Identifiers

PMID36708390
PMCPMC9884128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.