Evidence map›Paper›PMID 36708154›Full record

ArticleDrug delivery2023

The preparation and relative bioavailability of an artemisin in self-emulsifying drug delivery system.

Sijia Gao, Jingcai Chen, Wanqian Peng, Yang Yang, Yong Yang, Lei Hua, Yanlei Guo, Yunhong Wang, Xiaomei Zhang

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Article
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  7. Exploration of exogenous chlorogenic acid as a potential plant stimulant: enhancing physiochemical properties inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sijia GaoChongqing Academy of Chinese Materia Medica, Chongqing, China.
Jingcai ChenSchool of Pharmacy, Chengdu University of TCM, Chegndu, China.
Wanqian PengSchool of Pharmacy, Jiangxi University of Chinese Medicine, Jiangxi, China.
Yang YangChongqing Academy of Chinese Materia Medica, Chongqing, China.
Yong YangChongqing Academy of Chinese Materia Medica, Chongqing, China.
Lei HuaChongqing Academy of Chinese Materia Medica, Chongqing, China.
Yanlei GuoChongqing Academy of Chinese Materia Medica, Chongqing, China.
Yunhong WangChongqing Academy of Chinese Materia Medica, Chongqing, China.
Xiaomei ZhangChongqing Academy of Chinese Materia Medica, Chongqing, China.
Chongqing Academy of Chinese Materia Medica · CNChengdu University · CNJiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to demonstrate a method for improving the solubility and relative bioavailability of artemisinin using a self-emulsifying drug delivery system (SEDDS). The self-emulsifying drug load, solubility, and emulsifying time were used as the evaluation indices, based on a solubility test and a ternary phase diagram. Optimal Mixture Design in Design-Expert software was used to optimize the prescription of the artemisinin SEDDS. By determining the water distribution coefficient

Indexed as

ArtemisininsChemistry, PharmaceuticalAdministration, OralBiological AvailabilityDrug Delivery SystemsEmulsionsLactonesSolubilityartemisinartemisininArtemisininsEmulsionsLactonesArtemisininbioavailabilitycentral composite design-response surface methodologyself-emulsifying drug delivery systems (SEDDS)ternary phase diagram

Identifiers

PMID36708154
PMCPMC9888468
OpenAlexW4318332801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.