Evidence map›Paper›PMID 36707933›Full record

ArticleActa obstetricia et gynecologica Scandinavica2023

Association of postpartum medication practices with early breastfeeding cessation among mothers with chronic conditions: A prospective cohort study.

Natalie V Scime, Amy Metcalfe, Alberto Nettel-Aguirre, Suzanne C Tough, Kathleen H Chaput

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  7. High-risk pregnancy and risk of breastfeeding failure.The Journal of the Egyptian Public Health Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Natalie V ScimeDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-5811-7661
Amy MetcalfeDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-4449-9256
Alberto Nettel-AguirreCenter For Health and Social Analytics, National Institute for Applied Statistical Research, School of Mathematics and Statistics, University of Wollongong, Wollongong, New South Wales, Australia.ORCID 0000-0001-6604-0652
Suzanne C ToughDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Kathleen H ChaputDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-7596-6019
University of Calgary · CA

Funding

Canadian Institutes of Health Research Doctoral AwardCanadian Institutes of Health Research New Investigator AwardThe Alva FoundationUniversity of Calgary Department of Pediatrics
6 · The paper itself

Abstract

introductionUse of medications is a common concern for breastfeeding women, particularly when they are strongly needed or unavoidable to manage maternal chronic conditions. Yet the influence of medication usage patterns on breastfeeding duration in mothers with chronic conditions is unclear. The objective of this study was to examine whether postpartum medication practices were associated with shorter breastfeeding duration or earlier than planned breastfeeding cessation among mothers with chronic conditions. MATERIAL AND

methodsWe analyzed 346 mothers with chronic conditions enrolled in a prospective, community-based pregnancy cohort study (Alberta, Canada) who initiated breastfeeding after birth. Data were collected through self-report questionnaires spanning late pregnancy to 6 months postpartum. Based on reported use of preexisting medications while breastfeeding, women were classified as continuing medications (reference group), discontinuing one or more medications, or those who did not use preexisting medications. Cox proportional hazards regression was used to analyze the association of medication practices and overall breastfeeding duration in weeks. Logistic regression was used to analyze the association of medication practices and earlier than planned breastfeeding cessation. Multivariable models adjusted for demographic and health-related factors.

resultsOverall, 30.6% of women with chronic conditions stopped breastfeeding in the first 6 months, almost all of whom did so earlier than planned. In multivariable models, medication discontinuation was significantly associated with shorter breastfeeding duration (adjusted hazard ratio [HR] 1.67, 95% confidence interval [CI] 1.03-2.70) and earlier than planned breastfeeding cessation (adjusted odds ratio [OR] 1.85, 95% CI 1.01-3.42), whereas medication non-use was not associated with differences in breastfeeding outcomes.

conclusionsWomen with chronic conditions who discontinued preexisting medications while breastfeeding had significantly shorter breastfeeding duration and were less likely to meet their breastfeeding goals in the first 6 months postpartum compared to women who continued preexisting medications.

Indexed as

Breast FeedingMothersAlbertaCohort StudiesFemaleHumansInfantPostpartum PeriodPregnancyProspective StudiesSurveys and Questionnairesbreastfeedingchronic conditionsmedicationsprospective study

Identifiers

PMID36707933
PMCPMC10008275
OpenAlexW4318317823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.