Evidence map›Paper›PMID 36707867›Full record

ArticleJournal of ovarian research2023

LH level on ovulation trigger day has a different impact on the outcomes of agonist and antagonist regimens during in vitro fertilization.

Xi Luo, Bo Deng, Lei Li, Rui Ma, Xuancheng Mai, Ze Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of ovarian research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xi Luo *Department of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China. luoxi_ypfph@163.com.
Bo Deng *Department of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
Lei LiDepartment of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
Rui MaDepartment of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
Xuancheng MaiDepartment of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China. maixuancheng@163.com.
Ze WuDepartment of Reproductive Medicine, The First People's Hospital of Yunnan Province, Kunming, China. wuzes2010@163.com.
First People's Hospital of Yunnan Province · CNKunming University of Science and Technology · CN

Funding

National Natural Science Foundation of China 82260292Open Project of Yunnan Provincial Key Specialty of Gynecology 2022FKZDZK-13Open Project of Yunnan Provincial Reproductive and Obstetrics and Gynecology Clinical Medicine Center 2020LCZXKF-SZ08Open Project of Yunnan Provincial Reproductive and Obstetrics and Gynecology Clinical Medicine Center 2021LCZXXF-SZ01Open Project of Yunnan Provincial Reproductive and Obstetrics and Gynecology Clinical Medicine Center 2022LCZXKF-SZ16Yunnan Provincial Reproductive and Obstetrics and Gynecology Clinical Medicine Center zx2019-01-01
6 · The paper itself

Abstract

backgroundTo assess the impact of the luteinizing hormone level on ovulation trigger day (LHOTD) on in vitro fertilization (IVF) outcomes in gonadotropin-releasing hormone (GnRH) agonist and antagonist regimens during fresh embryo transfer cycles.

methodsA stepwise, progressive multivariate regression model was introduced to assess the effect of the LHOTD on clinical pregnancy and live birth rates. Mantel‒Haenszel stratification analysis was used to examine the association between the LHOTD and clinical outcomes with the antagonist regimen.

resultsThe LHOTD had different distributions in the agonist and antagonist regimens. The cycles were assigned into three LHOTD tertile groups. In the agonist regimen, compared with the 1

conclusionsThe LHOTD was profoundly suppressed in the agonist regimen, and its level was positively correlated with clinical pregnancy and live birth rates. In contrast, in the flexible antagonist regimen, the LHOTD was significantly higher than that in the agonist regimen and did not correlate with the outcome, except for women in the nonadvanced age group and those with an excessively suppressed LHOTD. Further investigation is required to determine the rationale for these findings.

Indexed as

Gonadotropin-Releasing HormoneOvulation InductionAdultFemaleFertilization in VitroHumansLuteinizing HormoneOvulationPregnancyPregnancy RateRetrospective StudiesGonadotropin-Releasing HormoneLuteinizing HormoneAssisted reproductive technologyClinical outcomeClinical pregnancyLive birthLuteinizing hormone

Identifiers

PMID36707867
PMCPMC9883898
OpenAlexW4318311184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.