Evidence map›Paper›PMID 36707524›Full record

ArticleSchizophrenia (Heidelberg, Germany)2023

Relapse prediction in schizophrenia with smartphone digital phenotyping during COVID-19: a prospective, three-site, two-country, longitudinal study.

Asher Cohen, John A Naslund, Sarah Chang, Srilakshmi Nagendra, Anant Bhan, Abhijit Rozatkar, Jagadisha Thirthalli, Ameya Bondre, Deepak Tugnawat, Preethi V Reddy and 8 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06043778 (Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India), which is not on this map. Cited by 49 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 6 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06043778 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India

TypeinterventionalSponsorHarvard Medical School (HMS and HSDM)Ran2026 to 2029Enrolled240ConditionsSchizophrenia, Schizophrenia and Related Disorders, Psychosocial FunctioningArmsCommunity care for People with Schizophrenia in India (COPSI), mindLAMP Mobile Application
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 6 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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  7. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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  11. Beyond RCTs-Better Research Designs and Methods for Psychosocial Efficacy Studies in Mental Health.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Asher CohenDivision of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
John A NaslundDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Sarah ChangDivision of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Srilakshmi NagendraDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.ORCID http://orcid.org/0000-0003-2855-5270
Anant BhanSangath, Bhopal, India.
Abhijit RozatkarDepartment of Psychiatry, AIIMS Bhopal, All India Institute of Medical Sciences Bhopal, Bhopal, India.ORCID http://orcid.org/0000-0002-8392-1395
Jagadisha ThirthalliDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Ameya BondreSangath, Bhopal, India.ORCID http://orcid.org/0000-0003-1359-4613
Deepak TugnawatSangath, Bhopal, India.
Preethi V ReddyDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.ORCID http://orcid.org/0000-0002-7229-1869
Siddharth DuttDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Soumya ChoudharyDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Prabhat Kumar ChandDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Vikram PatelDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Matcheri KeshavanDivision of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Devayani JoshiDivision of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Urvakhsh Meherwan MehtaDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
John TorousDivision of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. jtorous@bidmc.harvard.edu.ORCID http://orcid.org/0000-0002-5362-7937
National Institute of Mental Health and Neurosciences · INBeth Israel Deaconess Medical Center · USSangath · INHarvard University · USAll India Institute of Medical Sciences Bhopal · IN

Funding

Wellcome TrustWellcome Trust (Wellcome) 215843/Z/19/Z
6 · The paper itself

Abstract

Smartphone technology provides us with a more convenient and less intrusive method of detecting changes in behavior and symptoms that typically precede schizophrenia relapse. To take advantage of the aforementioned, this study examines the feasibility of predicting schizophrenia relapse by identifying statistically significant anomalies in patient data gathered through mindLAMP, an open-source smartphone app. Participants, recruited in Boston, MA in the United States, and Bangalore and Bhopal in India, were invited to use mindLAMP for up to a year. The passive data (geolocation, accelerometer, and screen state), active data (surveys), and data quality metrics collected by the app were then retroactively fed into a relapse prediction model that utilizes anomaly detection. Overall, anomalies were 2.12 times more frequent in the month preceding a relapse and 2.78 times more frequent in the month preceding and following a relapse compared to intervals without relapses. The anomaly detection model incorporating passive data proved a better predictor of relapse than a naive model utilizing only survey data. These results demonstrate that relapse prediction models utilizing patient data gathered by a smartphone app can warn the clinician and patient of a potential schizophrenia relapse.

Identifiers

PMID36707524
PMCPMC9880926
OpenAlexW4318219161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.