ArticleEuropean archives of psychiatry and clinical neuroscience2023
Neuropsychiatric post-acute sequelae of COVID-19: prevalence, severity, and impact of vaccination.
Article in European archives of psychiatry and clinical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Factors affecting the impact of COVID-19 vaccination on post COVID-19 conditions among adults: A systematic literature review.Human vaccines & immunotherapeutics · 2025Pooled it
- Evidence on the associations and safety of COVID-19 vaccination and post COVID-19 condition: an updated living systematic review.Epidemiology and infection · 2025Pooled it
- The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Incidence and burden of long COVID in Africa: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Post-COVID neuropsychiatric symptoms in India: Prevalence, risk factors, and persistence.Indian journal of psychiatry · 2026Article
- The fatigue spectrum in a community-based long haul COVID cohort.Sleep & breathing = Schlaf & Atmung · 2026Article
- Prior COVID-19 vaccination and cognitive outcomes after SARS-CoV-2 infection: a mini-review.Dementia & neuropsychologia · 2026Review
- Characteristics of Tinnitus in Patients Affected by COVID-19: A Systematic Review.International archives of otorhinolaryngology · 2025Review
- Correspondence: Neuropsychiatric post-acute sequelae of COVID-19.European archives of psychiatry and clinical neuroscience · 2025Article
- Article
- The Silent Syndrome of Long COVID and Gaps in Scientific Knowledge: A Narrative Review.Viruses · 2024Review
- Chronic post-COVID neuropsychiatric symptoms persisting beyond one year from infection: a case-control study and network analysis.Translational psychiatry · 2024Article
- SARS-CoV-2 induces blood-brain barrier and choroid plexus barrier impairments and vascular inflammation in mice.Journal of medical virology · 2024Article
- Unmasking the long-term effects: unravelling neuropsychiatric and neurological consequences of COVID-19.Annals of medicine and surgery (2012) · 2024Review
- Cognitive function and quantitative electroencephalogram analysis in subjects recovered from COVID-19 infection.BMC neurology · 2024Article
- Tinnitus and COVID-19: effect of infection, vaccination, and the pandemic.Frontiers in public health · 2024Article
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Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The potential long-term neuropsychiatric effects of COVID-19 are of global concern. This study aimed to determine the prevalence and predictors of neuropsychiatric post-acute sequelae of COVID-19 among Egyptian COVID-19 survivors and to study the impact of full vaccination before COVID-19 infection on the occurrence and severity of these manifestations. Three months after getting COVID-19 infection, 1638 COVID-19 survivors were screened by phone for possible neuropsychiatric sequelae. Subjects suspected to suffer from these sequelae were invited to a face-to-face interview for objective evaluation. They were requested to rate the severity of their symptoms using visual analogue scales (VAS). The mean age of participants was 38.28 ± 13 years. Only 18.6% were fully vaccinated before COVID-19 infection. Neuropsychiatric post-acute sequelae of COVID-19 were documented in 598 (36.5%) subjects, fatigue was the most frequent one (24.6%), followed by insomnia (16.4%), depression (15.3%), and anxiety (14.4%). Moderate and severe COVID-19 infection and non-vaccination increased the odds of developing post-COVID-19 neuropsychiatric manifestations by 2 times (OR 1.95, 95% CI = 1.415-2.683), 3.86 times (OR 3.86, 95% CI = 2.358-6.329), and 1.67 times (OR 1.67, 95% CI = 1.253-2.216), respectively. Fully vaccinated subjects before COVID-19 infection (n = 304) had significantly lesser severity of post-COVID-19 fatigue, ageusia/hypogeusia, dizziness, tinnitus, and insomnia (P value = 0.001, 0.008, < 0.001, 0.025, and 0.005, respectively) than non-vaccinated subjects. This report declared neuropsychiatric sequelae in 36.5% of Egyptian COVID-19 survivors, fatigue being the most prevalent. The effectiveness of COVID-19 vaccines in reducing the severity of some post-COVID-19 neuropsychiatric manifestations may improve general vaccine acceptance.
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