Evidence map›Paper›PMID 36707259›Full record

ArticleTrends in neurosciences2023

Invariant inhibition to calculate prediction errors?

Meaghan C Creed, Michaël Loureiro, Christian Lüscher

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Meaghan C CreedDepartment of Anesthesiology, Washington University in St Louis, St Louis, MO, USA; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA; Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA; Department of Biomedical Engineering, Washington University in St Louis, St Louis, MO, USA; Pain Center, Washington University in St Louis, St Louis, MO, USA.
Michaël LoureiroDepartment of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.
Christian LüscherDepartment of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland; Clinic of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, CH-1211 Geneva, Switzerland. Electronic address: christian.luscher@unige.ch.
University of Geneva · CHWashington University in St. Louis · US

Funding

Dissecting the role of ventral pallidal projections to nucleus accumbens in reward processingR01DA049924 · NIDA · WASHINGTON UNIVERSITY · PI CREED, MEAGHAN C · 2020 to 2024
$2.0M
NIDA NIH HHS R01 DA049924
6 · The paper itself

Abstract

The ventral tegmental area (VTA) has a pivotal role in motivated behavior. Much of the research on the VTA has focused on the mesocorticolimbic dopamine projections and their role in the computation of a 'reward prediction error' (RPE) for reward-guided learning. In a recent study, Zhou et al. report that VTA GABA neurons, the axons of which innervate the ventral pallidum (VP), have a unique role in signaling reward value to the basal ganglia and guiding reward seeking.

Indexed as

Basal GangliaVentral Tegmental AreaDopamineHumansRewardDopaminedopamineGABAreward prediction error

Identifiers

PMID36707259
OpenAlexW4318046550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.