Evidence map›Paper›PMID 36707232›Full record

ArticleGut2023

Cracking the host functional network involved in hepatitis B virus cccDNA biology.

Barbara Testoni, Alexander Ploss

Abstract readComment
In one paragraph

Article in Gut, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Barbara Testoni *INSERM U1052, Centre de recherche en Cancerologie de Lyon, Lyon, France aploss@princeton.edu barbara.testoni@inserm.fr.
Alexander Ploss *Molecular Biology, Princeton University, Princeton, New Jersey, USA aploss@princeton.edu barbara.testoni@inserm.fr.ORCID 0000-0001-9322-7252

Funding

Rational design and efficacy testing of vaccines against HCVR01AI168048 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Alexander Andrianov, Thomas R Fuerst · 2022 to 2026
$7.1M
Modeling immune impairments and pathogenesis in novel humanized mice for HBV-HIV co-infectionR01AI138797 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PLOSS, ALEXANDER, SU, LISHAN · 2018 to 2022
$3.9M
Mechanisms of hepatitis B virus cccDNA formationR01AI153236 · NIAID · PRINCETON UNIVERSITY · PI PLOSS, ALEXANDER · 2020 to 2024
$2.8M
Mechanisms coordinating the local and systemic resistance to pathogensR01AI168192 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Nevil John Singh · 2023 to 2026
$2.3M
Role of sub-activation-threshold TCR interactions in maintaining T cell memoryR01AI110719 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SINGH, NEVIL JOHN · 2015 to 2019
$2.1M
Mechanisms maintaining the self-awareness of peripheral T cellsR21AI149076 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SINGH, NEVIL JOHN · 2020 to 2021
$425k
JEDI negatively regulates TCR-signaling in chronically-stimulated T cellsR21AI126184 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SINGH, NEVIL JOHN · 2016 to 2017
$424k
Modifying T Cell Responses by Combinatorial Targeting of Negative regulatorsR56AI113313 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SINGH, NEVIL JOHN · 2014 to 2014
$384k
NIAID NIH HHS R01 AI110719NIAID NIH HHS R01 AI138797NIAID NIH HHS R01 AI153236NIAID NIH HHS R01 AI168048NIAID NIH HHS R01 AI168192NIAID NIH HHS R21 AI126184NIAID NIH HHS R21 AI149076NIAID NIH HHS R56 AI113313
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hepatitis BHepatitis B, ChronicBiologyDNA, CircularDNA, ViralHepatitis B virusHepatocytesHumansVirus ReplicationDNA, CircularDNA, Viralchronic viral hepatitishepatitis B

Identifiers

PMID36707232
PMCPMC10372188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.