Evidence map›Paper›PMID 36706842›Full record

ReviewGastroenterology2023

Controlling Gastric Cancer in a World of Heterogeneous Risk.

Robert J Huang, Monika Laszkowska, Haejin In, Joo Ha Hwang, Meira Epplein

Open access · bronzeAbstract readReview
In one paragraph

Review in Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 4 pooled it
30.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 4 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Burden of gastric cancer attributable to Helicobacter pylori in 27 countries from seven geographic regions in 2022.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Pooled it
  2. Global Progression Rates of Precursor Lesions for Gastric Cancer: A Systematic Review and Meta-Analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Diagnosing and grading gastric atrophy and intestinal metaplasia using semi-supervised deep learning on pathological images: development and validation study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Trial
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Monoclonal stool antigen test for diagnosingFrontiers in cellular and infection microbiology · 2026
    Article
  19. Artificial intelligence in gastric cancer risk assessment: expanding horizons for personalized surveillance in corpus atrophic gastritis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Robert J HuangDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California. Electronic address: rjhuang@stanford.edu.
Monika LaszkowskaGastroenterology, Hepatology, and Nutrition Service, Department of Subspecialty Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Haejin InRutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
Joo Ha HwangDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California.
Meira EppleinDuke University, Department of Population Health Sciences, and Cancer Risk, Detection, and Interception Program, Duke Cancer Institute, Durham, North Carolina.
Duke University · USMemorial Sloan Kettering Cancer Center · USRutgers, The State University of New Jersey · USStanford Medicine · USStanford University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Comparative modeling of gastric cancer health drivers and prevention in the US and globallyU01CA265729 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HUR, CHIN, YEH, JENNIFER M. · 2021 to 2025
$4.1M
Delineating the underlying reasons for the racial disparity in gastric cancer incidence in the United StatesR01CA267842 · NCI · DUKE UNIVERSITY · PI MEIRA EPPLEIN · 2022 to 2026
$3.3M
Project 2: Racial differences in host immune response and gastric carcinogenesis: Translating underlying biology to promote gastric cancer interceptionP20CA251657 · NCI · DUKE UNIVERSITY · PI POLLAK, KATHRYN I · 2020 to 2022
$3.2M
Research Education and Training CoreP30AG059304 · NIA · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI DONG, XINQI · 2018 to 2022
$3.1M
PRECISE - a PErsonalized Risk Score for gastrIc CancErK08CA252635 · NCI · STANFORD UNIVERSITY · PI HUANG, ROBERT JEFFREY · 2021 to 2025
$941k
A Targeted Approach to the Surveillance of Precursor Lesions for Gastric CancerK08DK125876 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI LASZKOWSKA, MONIKA · 2021 to 2025
$838k
NCI NIH HHS K08 CA252635NCI NIH HHS P20 CA251657NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA267842NCI NIH HHS U01 CA265729NIA NIH HHS P30 AG059304NIDDK NIH HHS K08 DK125876
6 · The paper itself

Abstract

Gastric cancer (GC) is a leading cause of global mortality but also a cancer whose footprint is highly unequal. This review aims to define global disease epidemiology, critically appraise strategies of prevention and disease attenuation, and assess how these strategies could be applied to improve outcomes from GC in a world of variable risk and disease burden. Strategies of primary prevention focus on improving the detection and eradication of the main environmental risk factor, Helicobacter pylori. In certain countries of high incidence, endoscopic or radiographic screening of the asymptomatic general population has been adopted as a means of secondary prevention. By contrast, identification and targeted surveillance of individuals with precancerous lesions (such as intestinal metaplasia) is being increasingly embraced in nations of low incidence. This review also highlights existing knowledge gaps in GC prevention as well as the role of emerging technologies for early detection and risk stratification.

Indexed as

Helicobacter InfectionsHelicobacter pyloriPrecancerous ConditionsStomach NeoplasmsEndoscopyGastric MucosaHumansIncidenceMetaplasiaRisk FactorsAtrophic GastritisGastric CancerHelicobacter pyloriIntestinal Metaplasia

Identifiers

PMID36706842
PMCPMC10270664
OpenAlexW4317929836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.