Evidence map›Paper›PMID 36706350›Full record

ArticleJCO global oncology2023

Hypofractionation in Breast Cancer Radiotherapy Across World Bank Income Groups: Results of an International Survey.

Melinda Mushonga, Jessica Weiss, Zhihui Amy Liu, Anna-Mary Nyakabau, Osama Mohamad, Bouchra Tawk, Fabio Y Moraes, Surbhi Grover, Mei Ling Yap, Eduardo Zubizarreta and 2 more

Open access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Global perspective on implementing ultra-hypofractionated radiation therapy in breast cancer: a survey-based analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 7 countries.

Melinda MushongaSally Mugabe Central Hospital, Harare, Zimbabwe.ORCID 0000-0002-3983-4892
Jessica WeissDepartment of Biostatistics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.ORCID 0000-0002-8679-9524
Zhihui Amy LiuDepartment of Biostatistics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Anna-Mary NyakabauDepartment of Oncology, Faculty of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.ORCID 0000-0001-6284-2252
Osama MohamadDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA.
Bouchra TawkGerman Cancer Research Consortium, Core Site Heidelberg, German Cancer Research Center, Heidelberg, Germany.
Fabio Y MoraesDepartment of Oncology, Division of Radiation Oncology, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0003-3407-9215
Surbhi GroverDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, United States; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-7443-5937
Mei Ling YapCollaboration for Cancer Outcomes, Research and Evaluation (CCORE), Ingham Institute, UNSW Sydney, Liverpool, Australia.ORCID 0000-0003-4216-2895
Eduardo ZubizarretaInternational Atomic Energy Agency, Vienna, Austria.
Yolande LievensGhent University Hospital and Ghent University, Ghent, Belgium.ORCID 0000-0002-9157-3730
Danielle RodinRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Canada.ORCID 0000-0001-8279-0621
University of Toronto · CACamden and Campbelltown Hospitals · AUGerman Cancer Research Center · DEGhent University Hospital · BEInternational Atomic Energy Agency · ATQueen's University · CAUniversity of California, San Francisco · USUniversity of Pennsylvania · USUniversity of Zimbabwe · ZW

Funding

Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
NCI NIH HHS K08 CA230170
6 · The paper itself

Abstract

purposeHypofractionated breast radiotherapy has been found to be equivalent to conventional fractionation in many clinical trials. Using data from the European Society for Radiotherapy and Oncology Global Impact of Radiotherapy in Oncology survey, we identified preferences for hypofractionation in breast cancer across World Bank income groups and the perceived facilitators and barriers to its use. MATERIALS AND

methodsAn international, electronic survey was administered to radiation oncologists from 2018 to 2019. Demographics, practice characteristics, preferred hypofractionation regimen for specific breast cancer scenarios, and facilitators and barriers to hypofractionation were reported and stratified by World Bank income groups. Variables associated with hypofractionation were assessed using multivariate logistic regression models.

resultsOne thousand four hundred thirty-four physicians responded: 890 (62%) from high-income countries (HICs), 361 (25%) from upper-middle-income countries (UMICs), 183 (13%) from low- and lower-middle-income countries (LLMICs). Hypofractionation was preferred most frequently in node-negative disease after breast-conserving surgery, with the strongest preference reported in HICs (78% from HICs, 54% from UMICs, and 51% from LLMICs,

conclusionPreference for hypofractionation varied for curative indications, with greater acceptance in earlier-stage disease in HICs and in later-stage disease in LLMICs. Targeted educational interventions and greater inclusivity in radiation oncology clinical trials may support greater uptake.

Indexed as

Breast NeoplasmsRadiation Dose HypofractionationDose Fractionation, RadiationFemaleHumansMastectomySurveys and Questionnaires

Identifiers

PMID36706350
PMCPMC10166450
OpenAlexW4318393038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.