Evidence map›Paper›PMID 36705860›Full record

Observational studyArchives of osteoporosis2023

Risk of osteoporotic fracture and refracture: the importance of index fracture site.

R Izquierdo-Avino, L Cebollada-Gadea, M Jordan-Jarque, D Bordonaba-Bosque, J A López-Cabanas

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Archives of osteoporosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Osteoporosis: Spotlight on current approaches to pharmacological treatment.Turkish journal of physical medicine and rehabilitation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R Izquierdo-AvinoFracture Liaison Service Unit, Department of Trauma and Orthopaedic Surgery, Hospital Provincial Nuestra Señora de Gracia, Zaragoza, Spain. drizquierdo@gmail.com.ORCID http://orcid.org/0000-0001-9654-8801
L Cebollada-GadeaFracture Liaison Service Unit, Department of Trauma and Orthopaedic Surgery, Hospital Provincial Nuestra Señora de Gracia, Zaragoza, Spain.
M Jordan-JarqueFracture Liaison Service Unit, Department of Trauma and Orthopaedic Surgery, Hospital Provincial Nuestra Señora de Gracia, Zaragoza, Spain.
D Bordonaba-BosqueStatistical and Methodological Support (SAME), Aragon Health Sciences Institute (IACS), Zaragoza, Spain.ORCID http://orcid.org/0000-0001-9444-606X
J A López-CabanasStatistical and Methodological Support (SAME), Aragon Health Sciences Institute (IACS), Zaragoza, Spain.ORCID http://orcid.org/0000-0001-9517-9426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study shows that patients aged 50 or more who have sustained an osteoporotic fracture have a significant risk of suffering a new fracture. Refracture risk is also increased when anatomic site of both index and subsequent fracture are the same. PURPOSE: The purpose of this study is to describe the profile of a patient sustaining a fragility fracture, the influence of the initial or index fracture on subsequent fracture risk and the role that anatomic site of index and subsequent fracture play on fracture risk.

methodsIn this retrospective observational cohort study, individuals aged ≥ 50 years who sustained at least one clinical fragility fracture were identified from the public health service register between January 1, 2014, and December 31, 2015. Two separate analysis cohorts were identified. Group 1 (index FF) included patients that sustained at least one clinical fragility fracture during the study period. Group 2 (subsequent FF) included those patients from group 1 who sustained at least one clinical subsequent fracture during the following 2 years after index fracture.

resultsA total of 11,986 fractures constituted group 1 (index FF), and 792 constituted group 2 (subsequent FF). The incidence of subsequent fractures was 6.61%, with a major percentage of them (36.99%) identified within the first 6 months following index FF. Hip was the most frequent site for index (30.09%) and subsequent fracture (34.85%). We found an increased risk mainly when anatomic site of index and subsequent FF are the same.

conclusionsSustaining a subsequent fracture after an index fracture is a common event in the population over age 50, more commonly occurring within 6 months of index fracture. Analysis of fracture site correlation shows that refracture risk is increased mainly when index and subsequent fracture site are the same.

Indexed as

Osteoporotic FracturesHumansIncidenceRetrospective StudiesRisk FactorsAnatomic fracture siteFracture riskImminent riskOsteoporotic fractures

Identifiers

PMID36705860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.