ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023
Sensibility, specificity, and accuracy of the Sinonasal Outcome Test 8 (SNOT-8) in patients with chronic rhinosinusitis (CRS): a cross-sectional cohort study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Climate and sino-nasal symptoms.International journal of biometeorology · 2026Article
- Thai Translation and Validation of Chronic Rhinosinusitis-Patient Reported Outcome (CRS-PRO).World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Correlation Between Nasal Anatomical Variants and SNOT-22 in Patients Affected by Odontogenic Sinusitis: A Retrospective Study.Journal of clinical medicine · 2025Article
- Part II - imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma?Frontiers in pharmacology · 2025Review
- Eustachian Tube Dysfunction Diagnostic Pathway-What Is the Current State of the Art and How Relevant Is Chronic Nasal Disease?Journal of clinical medicine · 2024Review
- Mendelian Randomization Reveals: Triglycerides and Sensorineural Hearing Loss.Bioengineering (Basel, Switzerland) · 2024Article
- Polyps' Extension and Recurrence in Different Endotypes of Chronic Rhinosinusitis: A Series of 449 Consecutive Patients.Journal of clinical medicine · 2024Article
- Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology.Journal of inflammation research · 2024Article
- Remodeling of Paranasal Sinuses Mucosa Functions in Response to Biofilm-Induced Inflammation.Journal of inflammation research · 2024Review
- Comprehensive Observational Study in a Large Cohort of Asthma Patients after Adding LAMA to ICS/LABA.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Post-traumatic olfactory dysfunction: a scoping review of assessment and rehabilitation approaches.Frontiers in neurology · 2023Article
- Down Regulation of EGF and AZGP1 Were Associated with Clinical Characteristics in Chronic Rhinosinusitis with Nasal Polyps: An Observation Study.Journal of inflammation research · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze as the primary endpoint the accuracy, sensitivity, and specificity of the SNOT-22 assessing CRS severity and to compare the results with a version of the SNOT-8 obtained from the nasal domain items.
methodsData were obtained from a prospective multicenter controlled study of dupilumab in adults with moderate-severe CRSwNP. EQUATOR and STROBE network guidelines were adopted. A multivariate logistic regression model was used to evaluate the accuracy of the model with the full (SNOT-22) and reduced (SNOT-8) item set to predict the severity outcome.
resultsSNOT-22 demonstrated an AUC of 0.885 (95% CI 0.825, - 0.945), and sensitivity and specificity of 91.49% (83.92-96.25%) and 69.23% (48.21-85.67%), respectively. Interestingly, after stepwise items elimination good outcomes were reported for SNOT-8, with an AUC of 0.818 (95% CI 0.744-0.892), achieving a sensitivity of 93.51% (85.49-97.86%) and specificity of 57.14% (40.96-72.28%).
conclusionPsychometric analyses support the accuracy, sensitivity, and specificity of the nasal domains of SNOT-22 to assess the impact on HRQoL in patients with CRSwNP.
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