Evidence map›Paper›PMID 36705559›Full record

ArticleRadiology. Imaging cancer2023

A Multicompartmental Diffusion Model for Improved Assessment of Whole-Body Diffusion-weighted Imaging Data and Evaluation of Prostate Cancer Bone Metastases.

Christopher C Conlin, Christine H Feng, Leonardino A Digma, Ana E Rodríguez-Soto, Joshua M Kuperman, Rebecca Rakow-Penner, David S Karow, Nathan S White, Tyler M Seibert, Michael E Hahn and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Radiology. Imaging cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Christopher C ConlinFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0003-4509-8702
Christine H FengFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0002-7790-9541
Leonardino A DigmaFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).
Ana E Rodríguez-SotoFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).
Joshua M KupermanFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).
Rebecca Rakow-PennerFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0002-2566-1978
David S KarowFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).
Nathan S WhiteFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0003-4564-2237
Tyler M SeibertFrom the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0002-4089-7399
Michael E Hahn *From the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).ORCID 0000-0002-8323-8174
Anders M Dale *From the Departments of Radiology (C.C.C., A.E.R.S., J.M.K., R.R.P., D.S.K., T.M.S., M.E.H., A.M.D.), Radiation Medicine and Applied Sciences (C.H.F., L.A.D., T.M.S.), and Neurosciences (A.M.D.), UC San Diego School of Medicine, 9452 Medical Center Dr, 4W 503, La Jolla, CA 92037; Human Longevity, Inc, San Diego, Calif (D.S.K.); CorTechs Labs, Inc, San Diego, Calif (N.S.W.); Department of Bioengineering, UC San Diego Jacobs School of Engineering, La Jolla, Calif (T.M.S.); and Halıcıoğlu Data Science Institute, UC San Diego, La Jolla, Calif (A.M.D.).
MACOM (United States) · US

Funding

Advanced diffusion MRI for evaluating early response to radiation treatment in cervical cancerR37CA249659 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Rebecca Ann Rakow-Penner · 2021 to 2026
$3.8M
STARLIGHT, The Next Generation X-ray Imaging TechnologyR44CA268468 · NCI · IMAGINE SCIENTIFIC, INC. · PI SILVER, ERIC · 2022 to 2023
$1.9M
Female Reproductive Tissue Mapping Center Data Analysis CoreU54HD104393 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PARAST, MANA M · 2020 to 2021
$1.2M
Improving assessment of prostate cancer bone metastases using advanced diffusion imagingK08EB026503 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEIBERT, TYLER MICHAEL · 2019 to 2022
$805k
Multi-atlas and whole body radiomics approaches for image-guided treatment of gynecologic cancersR01CA255780 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MELL, LOREN K. · 2021 to 2023
$759k
NCI NIH HHS R01 CA255780NCI NIH HHS R37 CA249659NCI NIH HHS R44 CA268468NIBIB NIH HHS K08 EB026503NICHD NIH HHS U54 HD104393
6 · The paper itself

Abstract

Purpose To develop a multicompartmental signal model for whole-body diffusion-weighted imaging (DWI) and apply it to study the diffusion properties of normal tissue and metastatic prostate cancer bone lesions in vivo. Materials and Methods This prospective study (

Indexed as

Bone NeoplasmsProstatic NeoplasmsAgedBayes TheoremDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMaleProspective StudiesBone MetastasesDiffusion Signal ModelDiffusion-weighted ImagingProstate CancerRestriction Spectrum ImagingWhole-Body MRI

Identifiers

PMID36705559
PMCPMC9896230
OpenAlexW4318263831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.