ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2023
Dysfunctional breathing and its impact on asthma control in children and adolescents.
Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Measurement properties of outcome measurement instruments for pediatric dysfunctional breathing: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- Validation of the Paediatric Nijmegen Questionnaire in Sweden: A Self-Screening Tool for Dysfunctional Breathing.The clinical respiratory journal · 2026Article
- Dysfunctional Breathing in Children: A Literature Review.Children (Basel, Switzerland) · 2024Review
- Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024Review
- Dysfunctional breathing and its impact on asthma control in children and adolescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2023Article
- Puzzled by dysfunctional breathing disorder(s)? Consider the Bayesian brain hypothesis!Frontiers in neuroscience · 2023Article
- [Consensus document for Severe Asthma. 2025 Update].Open respiratory archivesArticle
- Progress in diagnosis and treatment of difficult-to-treat asthma in children.Therapeutic advances in respiratory diseaseReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDysfunctional breathing (DB) has been shown to negatively affect asthma control in adults, but for children and adolescents, the knowledge is scarce. DB is among others characterized by dyspnea and hyperventilation. The Nijmegen Questionnaire (NQ) is often used as a marker for DB. We conducted a cross-sectional survey to estimate the prevalence of DB in patients with asthma in a pediatric outpatient clinic and to determine the impact of DB on asthma control.
methodsPatients between 10 and 17 years were invited to complete the NQ and the Asthma Control Questionnaire (ACQ) and report the use of beta2 agonist (β2). Spirometry data and prescribed asthma medications were noted from the patient record.
resultsThree hundred and sixty-three patients (180 boys) completed the survey. Sixty-seven patients (18%) scored ≥23 points in the NQ predicting DB. The DB group was older (median (range)) 15.6 (10.5-17.9) vs. 13.7 (10.0-17.9) years) (p < .01), and girls were overrepresented (84%) (p < .01). FEV1% exp. was higher in the DB group (mean (SD)) (89.4 (9.0) vs. 85.7 (11.8)) (p < .02). ACQ score (median (range)) (2.0 (0-4) vs. 0.6 (0-3.4)) (p < .01) and the use of β2 (median (range)) (2 (0-56) vs. 0 (0-20) puffs/week) (p < .01) were higher. Inhaled corticosteroid dose (mean (SD) (416 (160) vs. 420 (150) mcg) and the use of a second controller were equal between the groups.
conclusionDysfunctional breathing was a frequent comorbidity, especially in adolescent girls. DB correlated with poorer asthma control and higher use of β2 and may be an important cofactor in difficult-to-treat asthma.
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