ArticleFrontiers in nutrition2022
Birth outcomes, puberty onset, and obesity as long-term predictors of biological aging in young adulthood.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Associations between female reproductive factors and osteoarthritis in women ≥ 50 years old: An NHANES 1999-2018 analysis of more than 10,000 women.Immunologic research · 2025Article
- Association of longitudinal body mass index trajectories with phenotypic age acceleration: a cross-sectional study based on growth mixture modeling.GeroScience · 2025Article
- Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood.Translational psychiatry · 2025Article
- A Case for estradiol: younger brains in women with earlier menarche and later menopause.GigaScience · 2025Article
- Genetic Causal Association Between Skin Microbiota and Biological Aging: Evidence From a Mendelian Randomization Analysis.Journal of cosmetic dermatology · 2025Article
- Association between Gut Microbiota and Biological Aging: A Two-Sample Mendelian Randomization Study.Microorganisms · 2024Article
- Longitudinal study of epigenetic aging and its relationship with brain aging and cognitive skills in young adulthood.Frontiers in aging neuroscience · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Biological aging and particularly the deviations between biological and chronological age are better predictors of health than chronological age alone. However, the predictors of accelerated biological aging are not very well understood. The aim was to determine the role of birth outcomes, time of puberty onset, body mass index (BMI), and body fat in accelerated biological aging in the third decade of life. Methods: We have conducted a second follow-up of the Czech part of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC-CZ) prenatal birth cohort in young adulthood (52% male; age 28-30; Results: The deviations between biological and chronological age in young adulthood ranged from -2.84 to 4.39 years. Accelerated biological aging was predicted by higher BMI [in both early (R Conclusion: Our findings provide comprehensive support of the Life History Theory, suggesting that early life adversity might trigger accelerated aging, which leads to earlier onset of puberty but decreasing fitness in adulthood, reflected by more visceral fat and higher BMI. Our findings also suggest that reduction of BMI in young adulthood slows down biological aging.
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