Evidence map›Paper›PMID 36704786›Full record

ArticleFrontiers in nutrition2022

Effect of almond consumption on insulin sensitivity and serum lipids among Asian Indian adults with overweight and obesity- A randomized controlled trial.

Rajagopal Gayathri, Kuzhandhaivelu Abirami, Natarajan Kalpana, Valangaiman Sriram Manasa, Vasudevan Sudha, Shanmugam Shobana, Raman Ganesh Jeevan, Vasudevan Kavitha, Karthikeyan Parkavi, Ranjit Mohan Anjana and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Rajagopal GayathriDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Kuzhandhaivelu AbiramiDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Natarajan KalpanaDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Valangaiman Sriram ManasaDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Vasudevan SudhaDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Shanmugam ShobanaDepartment of Diabetes Food Technology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Raman Ganesh JeevanDepartment of Diabetes Food Technology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Vasudevan KavithaDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Karthikeyan ParkaviDepartment of Diabetes Food Technology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Ranjit Mohan AnjanaDepartment of Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Ranjit UnnikrishnanDepartment of Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Kuppan GokulakrishnanDepartment of Neurochemistry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, Karnataka, India.
D Annette BeatriceDepartment of Home Science, Women's Christian College, Chennai, Tamil Nadu, India.
Kamala KrishnaswamyDepartment of Foods Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Rajendra PradeepaDepartment of Research Operations, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Richard D MattesDepartment of Nutrition Science, College of Health and Human Sciences, Purdue University, West Lafayette, IN, United States.
Jordi Salas-SalvadóHuman Nutrition Unit, Department of Biochemistry and Biotechnology, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.
Walter WillettDepartment of Nutrition, Harvard School of Public Health, Boston, MA, United States.
Viswanathan MohanDepartment of Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Madras Diabetes Research Foundation · INChristian Medical College · INHarvard University · USNational Institute of Mental Health and Neurosciences · INPurdue University West Lafayette · USSpanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition · ESUniversity of Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asian Indians have an increased susceptibility to type 2 diabetes and premature coronary artery disease. Nuts, like almonds, are rich in unsaturated fat and micronutrients with known health benefits. Objectives: This study aimed to assess the efficacy of almonds for reduction of insulin resistance and improving lipid profile in overweight Asian Indian adults. Methods: This parallel-arm, randomized, controlled trial was conducted in Chennai, India on 400 participants aged 25-65 years with a body mass index ≥ 23 kg/m Results: A total of 352 participants completed the study. Significant improvement was seen in DIo [mean (95% CI) = + 0.7 mmol/L (0.1, 1.3); Conclusion: Daily consumption of almonds increased the intake of MUFA with decrease in carbohydrate calories and decreases insulin resistance, improves insulin sensitivity and lowers serum cholesterol in Asian Indians with overweight/obesity. These effects in the long run could aid in reducing the risk of diabetes and other cardiometabolic disease.

Indexed as

almondAsian–Indianinsulin resistanceinsulin sensitivityoverweight and obesityserum lipid

Identifiers

PMID36704786
PMCPMC9873375
OpenAlexW4315471461

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.