Trial reportIranian endodontic journal2021
The Effect of Adding Clonidine to Articaine and Epinephrine on Post-treatment Pain: A Randomized Clinical Trial Study.
Trial report in Iranian endodontic journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Evaluating the effect of amalgam fillings on caries detection in cone-beam computed tomography images.Dental research journal · 2024Article
- Accuracy of tooth-implant impressions: Comparison of five different techniques.Clinical and experimental dental research · 2023Review
- Stress Distribution in 5-Unit Fixed Partial Dentures with a Pier Abutment and Rigid and Nonrigid Connectors with Two Different Occlusal Schemes: A Three-Dimensional Finite Element Analysis.International journal of dentistry · 2023Article
- Evaluation of the effect of amalgam fillings on the diagnosis of proximal caries using cone-beam computed tomography technique.Dental research journal · 2023Article
- Comparative Efficacy of Analgesics for Pain Relief in Patients with Symptomatic Irreversible Pulpitis Prior to Emergency Endodontic Treatment: A Randomized Controlled Trial.Iranian endodontic journal · 2023Review
- The Effect of Ferrule/Crown Ratio and Post Length on the Applied Stress and Strain Distribution to the Endodontically Treated Maxillary Central Teeth: A Finite Element Analysis.Frontiers in dentistry · 2023Article
- Does a New Modification of the Two-Step Injection Technique for Inferior Alveolar Nerve Block Reduce Pain Compared to the Conventional Technique? A Randomized Clinical Trial.International journal of dentistry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Articaine is reported to have a fast onset and a short-acting pulpal anesthesia in inferior alveolar nerve blocks. Clonidine is an Materials and Methods: Our randomized clinical trial study enrolled one hundred patients with symptomatic irreversible pulpitis in mandibular molars. They were divided into two groups, each group received either 0.2 mL 150 µg/mL clonidine or distilled water added to 1.8 mL of 4% articaine with 1:100,000 epinephrine cartridge. The alveolar nerve block in the two groups was administered by the same clinician and the subject's pain scores were recorded at 6, 12, 24, 48 and 72 h post-operatively using a Heft-Parker visual analog scale. Data were analyzed using t, chi-square and repeated-measures ANOVA statistical tests. Results: The mean pain scores for clonidine group were significantly lower than control at all the time intervals after treatment ( Conclusion: Based on this randomized clinical trial study the addition of clonidine to the articaine/epinephrine solution using an inferior alveolar nerve block during root canal treatment in mandibular molars with irreversible pulpitis may be effective in reducing post-operative pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.