ArticleFrontiers in psychiatry2022
Sex- and genotype-dependent nicotine plus cue-primed reinstatement is enhanced in adolescent Sprague Dawley rats containing the human
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- The effect of mixed tobacco monoamine oxidase inhibitors in animal models relevant to tobacco dependence.Psychopharmacology · 2025Article
- "Unraveling the role ofReceptors (Basel, Switzerland) · 2025Article
- Dopamine and Norepinephrine Tissue Levels in the Developing Limbic Brain Are Impacted by the HumanInternational journal of molecular sciences · 2024Article
- Sub-chronic nicotine exposure influences methamphetamine self-administration and dopamine overflow in a sex-and genotype-dependent manner in humanizedFrontiers in pharmacology · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Rationale: Large-scale human candidate gene studies have indicated that a genetic variant (rs2304297) in the alpha(α)6 nicotinic acetylcholine receptor (nAChR) subunit, encoded by the Methods: Using CRISPR-Cas9 genomic engineering, we developed a humanized rat line with the human gene variant of the Results: For natural food rewards, nicotine self-administration, progressive ratio, and extinction, adolescent male and female (α6 Conclusion: Our findings support the
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