Evidence map›Paper›PMID 36704704›Full record

ArticleJID innovations : skin science from molecules to population health2023

Construction of a Secondary Enclosure for UVB Irradiation of Mice.

Justin Choi, Zachary A Bordeaux, Gabriella Braun, Cole Davis, Varsha Parthasarathy, Junwen Deng, Mathew T Taylor, Anusha Kambala, Hannah Cornman, Olusola Oladipo and 4 more

Open access · goldAbstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Topical GZ21T Inhibits the Growth of Actinic Keratoses in a UVB-Induced Model of Skin Carcinogenesis.JID innovations : skin science from molecules to population health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Justin ChoiDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zachary A BordeauxDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gabriella BraunDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.
Cole DavisDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.
Varsha ParthasarathyDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Junwen DengDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mathew T TaylorDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Anusha KambalaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hannah CornmanDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Olusola OladipoDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Martin P AlphonseDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Cameron E WestGenzada Pharmaceuticals, Hutchinson, Kansas, USA.
Shawn G KwatraDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Madan M KwatraDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.
Johns Hopkins University · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

UV irradiation is commonly used in murine models of skin cancers. Despite the popularity of using UVB rays to model photocarcinogenesis in animals, there is a lack of standardization in the secondary enclosures used to administer radiation. An appraisal of the literature also shows a general lack of details regarding the materials and procedures utilized in the fabrication of such enclosures. We present in this study a detailed overview of the construction of a UVB exposure chamber that successfully induces lesions in hairless mice. A standardized protocol for producing a UVB enclosure may reduce methodological variation in future studies seeking to investigate photocarcinogenesis in animals.

Identifiers

PMID36704704
PMCPMC9872852
OpenAlexW4298009625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.