Evidence map›Paper›PMID 36704502›Full record

SynthesisFrontiers in aging neuroscience2022

Effects of non-invasive brain stimulation on walking and balance ability in Parkinson's patients: A systematic review and meta-analysis.

Xinxin Zhang, Feiyue Jing, Yu'ang Liu, Jinyong Tang, Xianfeng Hua, Jialin Zhu, Haowen Tuo, Qihan Lin, Pincao Gao, Weiguo Liu

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. The effects of transcranial magnetic stimulation in motor symptoms of Parkinson's disease: an overview of systematic reviews with meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
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  14. Barefoot walking improves cognitive ability in adolescents.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xinxin ZhangCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Feiyue JingCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Yu'ang LiuCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Jinyong TangCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Xianfeng HuaCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Jialin ZhuCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Haowen TuoCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Qihan LinCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Pincao GaoCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Weiguo LiuCollege of Physical Education and Health, Guangxi Normal University, Guilin, China.
Guangxi Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate and contrast the effects of non-invasive brain stimulation (NIBS), including repeated transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), on walking and balance ability in patients with Parkinson's disease (PD). Methods: The PubMed, Embase, Medline, Cochrane, CNKI, and Chinese WanFang databases were searched up to June 2022. Quality assessment was performed using the Cochrane Collaboration's risk-of-bias guidelines, and the standardized mean differences (SMD) or mean differences (MD) for each outcome were calculated. Results: Among 32 eligible studies, including 1,586 participants were analyzed in this meta-analysis. The results of the meta-analysis showed that NIBS was effective in improving UPDRS-III scores (MD = -2.07; 95% CI, -2.62 to -1.53; Conclusion: NIBS benefits some walking ability variables but not balance ability in 36 patients with PD. The rTMS significantly improved UPDRS-III scores and TUGT time compared to tDCS. Further studies are needed to determine the optimal protocol and to illuminate effects based on the ideal target brain regions, stimulation intensity, timing, and type of intervention. Systematic review registration: http://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022350782.

Indexed as

meta-analysisnon-invasive brain stimulationParkinson’s diseaserepetitive transcranial magnetic stimulationtranscranial direct current stimulation

Identifiers

PMID36704502
PMCPMC9871558
OpenAlexW4315434076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.