Evidence map›Paper›PMID 36704478›Full record

ReviewFrontiers in cardiovascular medicine2022

Success rates, challenges and troubleshooting of left bundle branch area pacing as a cardiac resynchronization therapy for treating patients with heart failure.

Junmeng Zhang, Yimin Zhang, Yaxun Sun, Mengna Chen, Zefeng Wang, Changsheng Ma

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05985408 (Left Ventricular Septal Pacing Based Rescue CRT Versus Right Ventricular Apical Pacing Based CRT for Chronic Heart Failure), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05985408 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Left Ventricular Septal Pacing Based Rescue CRT Versus Right Ventricular Apical Pacing Based CRT for Chronic Heart Failure: a Randomized Controlled Trial

TypeinterventionalSponsorFu Wai Hospital, Beijing, ChinaRan2023 to 2025Enrolled40ConditionsHeart Failure, Cardiac Resynchronization Therapy, Left Ventricular Septal Pacing, Right Ventricular Septal PacingArmsleft ventricular septal pacing, right ventricular apical pacing
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Integral Role of Cardiac Imaging in the Electrophysiology Field.The Journal of innovations in cardiac rhythm management · 2025
    Review
  5. Article
  6. Learning Curve for Left Bundle Branch Area Pacing Lead Implantation.The Journal of innovations in cardiac rhythm management · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Junmeng ZhangDepartment of Cardiology, Beijing Huaxin Hospital, Tsinghua University, Beijing, China.
Yimin ZhangDepartment of Cardiology, Beijing Huaxin Hospital, Tsinghua University, Beijing, China.
Yaxun SunDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Mengna ChenDepartment of Cardiology, Beijing Huaxin Hospital, Tsinghua University, Beijing, China.
Zefeng WangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Changsheng MaDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Beijing Hua Xin Hospital · CNCapital Medical University · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) is an important treatment of heart failure patients with reduced left ventricular ejection fraction (LVEF) and asynchrony of cardiac electromechanical activity. Left bundle branch area pacing (LBBaP) is a novel physiological pacing modality that appears to be an effective method for CRT. LBBaP has several advantages over the traditional biventricular-CRT (BiV-CRT), including a low and stable pacing capture threshold, a high success rate of implantation, a short learning curve, and high economic feasibility. However, LBBaP is not suitable for all heart failure patients needing a CRT and the success rates of LBBaP in heart failure patients is lower because of myocardial fibrosis, non-specific intraventricular conduction disturbance (IVCD), enlargement of the right atrium or right ventricle, etc. In this literature review, we summarize the success rates, challenges, and troubleshooting of LBBaP in heart failure patients needing a CRT.

Indexed as

cardiac resynchronization therapyheart failureleft bundle branch area pacingsuccess ratestroubleshooting

Identifiers

PMID36704478
PMCPMC9872722
OpenAlexW4315433126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.