Evidence map›Paper›PMID 36704289›Full record

ArticleHeliyon2023

High cytotoxicity of a degraded TBBPA, dibromobisphenol A, through apoptotic and necrosis pathways.

Keitaro Suyama, Hitoshi Kesamaru, Takashi Okubo, Kazumi Kasatani, Keisuke Tomohara, Ayami Matsushima, Takeru Nose

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keitaro SuyamaFaculty of Arts and Science, Kyushu University, Fukuoka, 819-0395, Japan.
Hitoshi KesamaruDepartment of Chemistry, Faculty and Graduate School of Science, Kyushu University, Fukuoka, 819-0395, Japan.
Takashi OkuboDepartment of Chemistry, Faculty and Graduate School of Science, Kyushu University, Fukuoka, 819-0395, Japan.
Kazumi KasataniDepartment of Chemistry, Faculty and Graduate School of Science, Kyushu University, Fukuoka, 819-0395, Japan.
Keisuke TomoharaFaculty of Arts and Science, Kyushu University, Fukuoka, 819-0395, Japan.
Ayami MatsushimaDepartment of Chemistry, Faculty and Graduate School of Science, Kyushu University, Fukuoka, 819-0395, Japan.
Takeru NoseFaculty of Arts and Science, Kyushu University, Fukuoka, 819-0395, Japan.
Kyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Halogenated flame retardants comprising bisphenol A (BPA) derivatives, such as tetrabromobisphenol A (TBBPA), have been studied their adverse effects on human health. However, despite the fact that these halogenated BPAs are easily degraded in the environment, the risks to living organisms due to these degraded products have mostly been overlooked. To evaluate the potential toxicity of degraded TBBPAs and related compounds, we examined the cytotoxicity of halogenated bisphenol A derivatives possessing one to four halogen atoms

Indexed as

CytotoxicityHalogenationHeLa cellLDH release assayMTT assayTetrabromobisphenol A

Identifiers

PMID36704289
PMCPMC9871217
OpenAlexW4316506424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.