Evidence map›Paper›PMID 36704077›Full record

ArticleMovement disorders clinical practice2023

Functional Movement Disorders and Deep Brain Stimulation: A Multi-Center Study.

Luca Marsili, Elizabeth G Keeling, Ricardo Maciel, Maria Fiorella Contarino, Rodi Zutt, Michael S Okun, Leonardo Almeida, Wissam Deeb, Drew Kern, Daniel Macias-Garcia and 5 more

Open access · greenAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Functional ballistic movements.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 4 countries.

Luca MarsiliGardner Family Center for Parkinson's disease and Movement Disorders Cincinnati Ohio USA.ORCID https://orcid.org/0000-0002-6438-9911
Elizabeth G KeelingSchool of Life Sciences Arizona State University Tempe Arizona USA.
Ricardo MacielEdmond J. Safra Program in Parkinson's Disease Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN Toronto Ontario Canada.
Maria Fiorella ContarinoDepartment of Neurology Leiden University Medical Center Leiden The Netherlands.
Rodi ZuttDepartment of Neurology Haga teaching Hospital The Hague The Netherlands.
Michael S OkunDepartments of Neurology and Neurosurgery Norman Fixel Institute for Neurological Diseases, University of Florida Gainesville Florida USA.
Leonardo AlmeidaDepartments of Neurology and Neurosurgery Norman Fixel Institute for Neurological Diseases, University of Florida Gainesville Florida USA.
Wissam DeebDepartments of Neurology and Neurosurgery Norman Fixel Institute for Neurological Diseases, University of Florida Gainesville Florida USA.
Drew KernDepartments of Neurology and Neurosurgery University of Colorado School of Medicine Aurora Colorado USA.ORCID https://orcid.org/0000-0001-7317-3787
Daniel Macias-GarciaUnidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla Seville Spain.
Fatima CarrilloUnidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla Seville Spain.
Pablo MirUnidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla Seville Spain.ORCID https://orcid.org/0000-0003-1656-302X
Aristide MerolaDepartment of Neurology The Ohio State Wexner Medical Center Columbus Ohio USA.
Alberto J EspayGardner Family Center for Parkinson's disease and Movement Disorders Cincinnati Ohio USA.
Alfonso FasanoEdmond J. Safra Program in Parkinson's Disease Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN Toronto Ontario Canada.ORCID https://orcid.org/0000-0001-5346-0180
Biomedical Research Networking Center on Neurodegenerative Diseases · ESUniversity of Florida Health · USCentre for Movement Disorders · CAUniversity of Toronto · CABarrow Neurological Institute · USHaga Hospital · NLLeiden University Medical Center · NLThe Ohio State University Wexner Medical Center · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Functional movement disorders (FMD) are a commonly under-recognized diagnosis in patients with underlying neurodegenerative diseases. FMD have been observed in patients undergoing deep brain stimulation (DBS) for Parkinson's disease (PD) and other movement disorders. The prevalence of coexisting FMD among movement disorder-related DBS patients is unknown, and it may occur more often than previously recognized. Methods: We retrospectively assessed the relative prevalence and clinical characteristics of FMD occurring post-DBS, in PD and dystonia patients (FMD+, n = 29). We compared this cohort with age at surgery-, sex-, and diagnosis-matched subjects without FMD post-DBS (FMD-, n = 29). Results: Both the FMD prevalence (0.2%-2.1%) and the number of cases/DBS procedures/year varied across centers (0.15-3.65). A total of nine of 29 FMD+ cases reported worse outcomes following DBS. Although FMD+ and FMD- manifested similar features, FMD+ showed higher psychiatric comorbidity. Conclusions: DBS may be complicated by the development of FMD in a subset of patients, particularly those with pre-morbid psychiatric conditions.

Indexed as

deep brain stimulationfunctional movement disorderssurgery

Identifiers

PMID36704077
PMCPMC9847284
OpenAlexW4307918777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.