Evidence map›Paper›PMID 36703820›Full record

ArticleFrontiers in public health2022

High risk of unsuccessful treatment outcome in migrant population with tuberculosis: Data from three Italian hospitals.

Francesco Di Gennaro, Sergio Cotugno, Massimo Fasano, Aurelia Ricciardi, Luigi Ronga, Rossana Lattanzio, Anna Grimaldi, Davide Fiore Bavaro, Marianna Ciarallo, Stefania Garzone and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Managing tuberculosis infection among migrants from high-incidence tuberculosis countries: challenges, strategies and recommendations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  7. Article
  8. Article
  9. Strengthening Tuberculosis Control Among Migrant Workers.Tropical medicine and infectious disease · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Francesco Di GennaroClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Sergio CotugnoClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Massimo FasanoUnità Operativa Complessa (UOC) Infectious Diseases Azienda Sanitaria Locale Bari (ASL BA), Bari, Italy.
Aurelia RicciardiClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Luigi RongaMicrobiology and Virology Unit, University Hospital Policlinico, University of Bari, Bari, Italy.
Rossana LattanzioClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Anna GrimaldiChemical-Clinical and Microbiological Research Unit, ASL BA, Bari, Italy.
Davide Fiore BavaroClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Marianna CiaralloInfectious Diseases Unit, Department of Clinical and Surgical Sciences, University of Foggia, Foggia, Italy.
Stefania GarzoneMicrobiology and Virology Unit, University Hospital Policlinico, University of Bari, Bari, Italy.
Giuseppina De IacoClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Giacomo GuidoClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Josè Ramon FioreInfectious Diseases Unit, Department of Clinical and Surgical Sciences, University of Foggia, Foggia, Italy.
Gaetano BrindicciClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Carmen Rita SantoroClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
Salvatore SicaInfectious Diseases Unit, Department of Clinical and Surgical Sciences, University of Foggia, Foggia, Italy.
Tiziana Loredana IacovazziUnità Operativa Complessa (UOC) Infectious Diseases Azienda Sanitaria Locale Bari (ASL BA), Bari, Italy.
Teresa Antonia SantantonioInfectious Diseases Unit, Department of Clinical and Surgical Sciences, University of Foggia, Foggia, Italy.
Annalisa SaracinoClinic of Infectious Diseases, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro," Bari, Italy.
University of Bari Aldo Moro · ITUniversity of Foggia · ITASL Roma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tuberculosis (TB) remains an unresolved global health problem and vulnerable groups such as migrants remain the most affected with a higher risk of worse outcomes. The aim of this study was to evaluate clinical features, outcomes, and adverse events in migrant and native Italian patients admitted to three Italian hospitals in Southern Italy in order to assess differences and targeted strategies. Methods: We performed a retrospective study on TB patients admitted between January 1, 2013, and December 31, 2021, in three Apulia hospitals. Two logistic regression models were used, with the dependent variables being (I) unsuccessful treatment (died, loss to follow-up, and failed treatment) and (II) adverse events. Results: We enrolled 543 consecutive patients admitted at three Italian hospitals with a diagnosis of TB during the study period, of them 323 (59.5%) were migrants and 220 Italian patients. The treatment success rate in the migrant group was 44.9% (137/305), while in the non-migrant group was 97.1% (203/209). Independent factors of unsuccess treatment (death, failure or loss to follow up) were: migrant status (O.R. = 11.31; 95% CI 9.72-14.23), being male (O.R. = 4.63; 95% CI 2.16-6.10), homelessness (O.R. = 3.23; 95% CI 2.58-4.54), having a MDR (Multidrug-resistant) (O.R = 6.44; 95% CI 4.74-8.23), diagnostic delay (O.R. = 3.55; 95% CI 1.98-5.67), and length of hospitalization (O.R. = 3.43; 95% CI 1.88-5.87). While, age >65 ys (O.R. = 3.11; 95% CI 1.42-4.76), presence of extrapulmonary TB (O.R. = 1.51; 95% CI 1.31-2.18), monoresistance (O.R. = 1.45; 95% CI 1.25-3.14) and MDR pattern (O.R. = 2.44; 95% CI 1.74-5.03) resulted associated with adverse events. Conclusion: Migrant population is at high risk of unsuccessful treatment (death, loss to follow-up, and treatment failure). Policies targeted specifically to this group are needed to really impact and improve their health status and also to contain the TB burden.

Indexed as

TuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsDelayed DiagnosisFemaleHospitalsHumansItalyMaleRetrospective StudiesTreatment OutcomeAntitubercular Agentsanti-tubercular treatmenthigh risk of treatment failurelost-to-follow-up (LTFU)migrant populationstuberculosisvulnerables

Identifiers

PMID36703820
PMCPMC9871451
OpenAlexW4315434042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.