ArticleFrontiers in public health2022
Anticipating Unipolar Depression and Bipolar Depression in young adult with first episode of depression using childhood trauma and personality.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 11 citations in OpenAlex.
- Childhood trauma and impulsive behaviors: the multiple chain mediating effects of neuroticism, stress perception and depression.BMC psychology · 2026Article
- The impact of physical exercise on depression among college students: the mediating role of core self-evaluation and meaning in life.Frontiers in psychology · 2026Article
- The Impact of Asthma Control on the Clinical and Depressive Symptoms in Pediatric Asthma Patients.Actas espanolas de psiquiatria · 2025Article
- Childhood maltreatment influences coping in youths with major depression and bipolar depression through resilience and impulsivity.Scientific reports · 2025Article
- Associations between childhood maltreatment and personality traits in individuals with and without depression: a CTQ-based assessment.BMC psychology · 2025Article
- Multidimensional EEG features integration with feature selection strategy for precision diagnosis of depressive disorders.Frontiers in psychiatry · 2025Article
- Impact of childhood trauma on cognitive function in patients with bipolar disorder.Frontiers in psychiatry · 2025Article
- Impact pathways of personality and psychosocial stress on depression among adult community residents in China: a fuzzy-set qualitative comparative analysis.Frontiers in psychology · 2024Article
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Authors and funding
12 authors at 5 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: Relevant research focusing on young adults with Unipolar Depression (UD) and Bipolar Depression (BD) is limited. The current research aims to investigate childhood trauma and personality traits in young adults with UD and BD. Methods: Two hundred and thirty-five patients in a first depressive episode (diagnosed UD and BD), 16-25 years old, were recruited from Second Xiangya Hospital. And 79 healthy controls (HC) were recruited from the community to form the comparison group. Patients' childhood trauma was measured by the Childhood Trauma Questionnaire (CTQ), and personality was measured by Eysenck Personality Inventory (EPI). The Kruskal-Wallis test was used to compare depression, anxiety, CTQ, and EPI scores between the HC ( Results: Compared with HC, mood disorders had more severe anxiety and depression symptoms, and higher CTQ. Emotional abuse (OR = 1.47; 95% CI = 1.08-2.01), emotional neglect (OR = 1.24; 95% CI = 1.05-1.46), and neuroticism (OR = 1.25; 95% CI = 1.16-1.35) were associated with significantly increased odds of mood disorders. Whereas, higher extraversion scores were a protective factor for mood disorders. Compared with UD, BD had more severe anxiety symptoms, and higher CTQ, than extraversion and neuroticism personality scores. Anxiety (OR = 1.06; 95% CI = 1.02-1.08) and extraversion (OR = 1.05; 95% CI = 1.03-1.09) were associated with significantly increased odds of BD. Conclusion: Interventions to prevent childhood trauma may improve young adults' mental health. Using childhood trauma and personality to anticipate BD and UD creates more accurate treatment for young adults with first depression.
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