ArticleFrontiers in oncology2022
Case report: Clinical highlights and radiological classification of IgG4-related spinal pachymeningitis: A rare case series and updated review of the literature.
Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- IgG4-related spinal hypertrophic pachymeningitis: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Article
- IgG4-Related Disease Strikes the Cervical Spine: First Description of a Rare Cause for C1 Destruction and Tetraparetic Stenosis.Reports (MDPI) · 2026Article
- Surgical management of recurrent spinal hypertrophic pachymeningitis: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- IgG4-related disease presenting as hypertrophic pachymeningitis.Clinical rheumatology · 2025Article
- Long-Term Clinical Landscapes of Spinal Hypertrophic Pachymeningitis With Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.Neurology · 2025Article
- Clinical features of immunoglobulin G4-related spinal pachymeningitis.Frontiers in human neuroscience · 2025Article
- Intrathecal IgG4 synthesis in IgG4 related spinal hypertrophic pachymeningitis: a case report.Neurological research and practice · 2024Article
- A case of IgG4-related disease manifesting as a spinal epidural mass.BJR case reports · 2024Article
- A case report of Immunoglobulin-G4-related hypertrophic sclerosing pachymeningitis.Radiology case reports · 2024Article
- Article
- Cervical myelopathy caused by IgG4-related hypertrophic spinal pachymeningitis: Case report and a descriptive review of the literature.Brain & spine · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Hypertrophic pachymeningitis associated with immunoglobulin G4-related disease (IgG4-RD) has been rarely reported, and there is little information and no clear consensus on the management of IgG4-related spinal pachymeningitis (IgG4-RSP). The present study described its possible clinical features, including the symptoms, imaging, treatment and prognosis of patients with IgG4-RSP. Methods: We report three patients who presented with progressive neurological dysfunction due to spinal cord compression. Relevant articles were searched from the PubMed, Web of Science, and Embase databases, and the resulting literature was reviewed. Results: The literature review provided a summary of 45 available cases, which included three cases from our center. Progressive worsening of neurological impairment was observed in 22 patients (48.9%). The lesions involved the thoracic spine ( Conclusion: The number of reported cases of IgG4-RSP remains limited, and patients often have progressive worsening of their neurological symptoms. The features of masses identified on the MRI should be considered. The prognosis was better with decompression surgery combined with immunosuppressive therapy. Long-term corticosteroid treatment and steroid-sparing agent maintenance therapy should be ensured. A systemic examination is recommended to identify the presence of other pathologies.
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